ABSTRACTS from 16th International COnference on ... - CRRT Online

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<strong>ABSTRACTS</strong> FROM 17 TH INTERNATIONAL CONFERENCE ON CRRT, SAN DIEGO, FEB 14-17, 2012 Background: High-volume hemofiltration (HVHF) may improve the prognosis of patients by non-selective removal of inflammatory mediators and cytokines and reducing the systemic inflammatory response on organ damage. Since the timing of HVHF may impacts on the prognosis of the patients, early intervention of HVHF is very crucial. Objective: To assess the effects of the timing of HVHF on the elderly patients with septic shock. Methods: 21 cases of elderly patients with septic shock (mean age 78 ± 6.8 years) were observed. According to the timing of HVHF (the rate of UF was 6ml/kg/hr ),those patients were divided into two groups,Group A (n = 8) treated with HVHF during early 6 hours resuscitation and Group B (13 cases) treated with HVHF after early 6 hours resuscitation.The effects to be studied of HVHF were the changes of vital signs, the difference of APACHE-Ⅱ score, SOFA score, the dosage of vasoactive drugs in h, 24h, 48h, 72h and the survival cases of 28 days. Results: Treated with HVHF after 24h, 48h, 72h, APACHE-Ⅱ score in group A and group B were (23.5 ± 4.8,18.5 ± 4.,18.1 ± 4.3) and 26.8±4.2, 24.3±3.8、23.8±5.1)(P
<strong>ABSTRACTS</strong> FROM 17 TH INTERNATIONAL CONFERENCE ON CRRT, SAN DIEGO, FEB 14-17, 2012 ventilation rate was 73.2%, vasoactive drug was 63.8%. The average SAPS3 was 78.4 ± 15.9 and the average APACHE II score was 26.5 ± 4.3. The variables influencing mortality on univariate analysis were SAPS3 and BNP, the number of organ dysfunction. Conclusion: Very important prognostic factors were SAPS3 and the elevation of BNP in this study. Large scaled, prospective randomized multi-center trials are needed to confirm the prognostic factor. 26. Citrate in a Small Intensive Care Unit (ICU) in the Netherlands; The Better Way for Dialysis? Els L Van Assche 1 Elkerliek Ziekenhuis Background: Renal replacement therapy (RRT) is performed in order to prevent and treat complications of acute kidney injury. Small ICU’s are challenged to optimize the procedures. Since regional citrate anticoagulation is proven an effective and safe method for continuous RRT, we replaced the heparin protocol and introduced citrate as the new anticoagulants. Methods: We conducted a retrospective observational study to compare the citrate and heparin protocol. We studied mortality, filter survival time, transfusion of packed cells (PC) frequency and other complications during dialysis. We reviewed the medical records of the 63 patients who had continuous RRT <strong>from</strong> January 27 until September 211. We used our patient data management system to compare the data <strong>from</strong> the citrate group to the data <strong>from</strong> the heparin group. 18 patients were excluded with insufficient data and 22 filters which were interrupted intentionally were also excluded. Results: A total of 45 patients were included in this study, 21 in the heparin group and 24 in the citrate group. In the patients who received heparin, 112 filters were used, with a mean of 5 filters per patient and median filter time of 13 hours. In patients who received citrate, 66 filters were used, with a mean of 4 filters per patient and median filter time of 56 hours. In the heparin group 86 transfusions were needed in 18 patients, 7 patients needed more than 2 PC during dialysis treatment. In the citrate group 26 transfusions were given to 11 patients; 3 patients needed more than 2 transfusions. Only the heparin protocol was interrupted, 8 times, for complications. The mortality in the ICU was worse in the citrate group; 54% compared to 26 % in the heparin group. Conclusions: Although mortality was higher in the citrate group, we found no complications so we consider citrate a safe anticoagulans for RRT. The higher mortality can be explained by the higher Apache scores. The median filter time proves citrate to be superior to heparin. 27. Ultrafiltration in Continuous Renal Replacement Therapy: Is Prescribed Delivered ? William E Weber, Sagar S Patel, Nand K Wadhwa Stony Brook University, Stony Brook, NY Background: Hypervolemia <strong>from</strong> aggressive fluid resuscitation in critically ill patients with acute kidney injury (AKI) may contribute to adverse outcomes. Continuous renal replacement therapy (CRRT) can effectively achieve fluid management goals in hemodynamically unstable patients with AKI. Methods: We collected data on physician prescription orders compared to actual delivered treatments to assess the delivered CRRT therapy in critically ill patients with AKI. 18 patients (mean age 53 + 17 years (SD); 12 males, 6 142
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CRRT 2012 SEVENTEENTH INTERNATIONAL
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FACULTY DISCLOSURES CRRT 2012 Facul
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CRRT 2012 ORGANIZING COMMITTEE USA
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CRRT 2012 FACULTY Patrick Honoré,
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ACKNOWLEDGEMENTS CRRT 2012 ACKNOWLE
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PLENARY SESSIONS CRRT 2012 PROGRAM/
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WORKSHOPS CRRT 2012 PROGRAM/INDEX T
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WORKSHOPS CRRT 2012 PROGRAM/INDEX W
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POSTER ABSTRACTS C
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POSTER ABSTRACTS C
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NURSING FORUM LUNCHEON Communicatio
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Nutritional Support in ICU Patients
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Educational Objectives: The Endothe
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SPECIAL LECTURE Engineering Critica
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Nishimura R, Ornato JP, Page RL, Ri
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Do Vasoactive Drugs and Fluids Impr
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Blood Transfusions are Important fo
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Thinking Outside of the Box: A Nove
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Nursing Forum 2 Luncheon Benchmarki
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4. Mori K, Lee HT, Rapoport D, Drex
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Differential Diagnosis of AKI: Can
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Myocardial Stunning and Brain Edema
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4. Udy A, Roberts JA, Lipman J. Wha
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CRRT and ECMO: Techniques and Outco
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Management of Severe Heart Failure:
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Avoiding Anticoagulation for CRRT:
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Improving Outcomes from</st
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The Changing Face of AKI: Snapshots
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Alkaline Phosphatase Peter Pickkers
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creatinine (Cr) was measured using
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Surveillance and Early Recognition
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therapy admitted to general intensi
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A01 Assessing the Microcirculation
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A01 Assessing the Microcirculation
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C03 Critical Care Pharmacology: Vas
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D04 Biomarkers 1: Principles and Ap
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6. Ferguson JW, Dover AR, Chia S, C
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G07 Fluids and Solutions in the Cri
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A09 Vascular Access /Membrane and C
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A09 Vascular Access /Membrane and C
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C11 Critical Care Management: Nutri
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D12 Biomarkers 2: Application in AK
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Educational Objectives: E13 Liver a
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Page 114 and 115: E29 Heart Failure and Cardio-Renal
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Page 118 and 119: H32 Withdrawing & Withholding Suppo
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