ABSTRACTS from 16th International COnference on ... - CRRT Online

The Changing Face of AKI: Snapshots <strong>from</strong> Around the World
Brazil, India, Japan, Canada, Australia, USA
Educational Objectives:
1. Highlight the complexity of AKI in Australia
Zoltan Endre MD, PhD
8:30-9:30
Friday, February 17
Content Description:
Two cases of AKI will be described. Neither resulted <strong>from</strong> ischemia-reperfusion injury. Even ischemic injury on
our population tends to occur in patients with significant comorbidity.
Educational Objectives:
Vishnu Bhotla Sivakumar MD, DM,
DNB, FISN,FR
1)PRESENTATION OF CLINICAL DETAILS OF A PATIENT OF ACUTE KIDNEY INJURY FOLLOWING
HAIR DYE INGESTION
2) TO DISCUSS THE PATHOGENESIS
3) MANAGEMENT
Content Description:
ACCIDENTAL OR INTENTIONAL INGESTION OF HAIR DYE IS INCREASING IN CERTAIN PARTS OF
AFRICA AND INDIA .
THE IMPORTANT TOXIC COMPONENT IDENTIFIED IN HAIR DYE POISONING IS PARAPHENYLENE-
DIAMINE(PPD).
FOLLOWING INGESTION IT RESULTS IN SWELLING OF ORAL CAVITY , TONGUE , AND CERVICAL
REGION . THIS RESULTS IN DIFFUCULITY IN SWALLOWING AND BREATHING. THIS OFTEN
NECESSITATES VENTILATORY SUPPORTS AND TRACHEOSTOMY.
THIS ALSO RESULTS IN PAINFUL SWELLING OF THE LIMBS DUE TO RHABDOMYOLYSIS.SOME-
TIMES SHOCK ALSO ACCOMPANIES. CARDIOTOXICITY LEADS TO ARRYTHMIAS , MYOCARDITIS
AND FAILURE
HYPOTENSION, MYOGLOBINURIA , HEMOLYSIS AND DIRECT TOXICITY RESULT IN ACUTE KID-
NEY INJURY.IT ALSO PRODUCES HEPATIC INJURY . MANAGEMENT INCLUDES GENERAL SUP-
PORTIVE MEASURES , RENAL REPLACEMENT IN ACUTE KIDNEY INJURY , AND VENTILATORY
SUPPORT FOR RESPIRATORY DIFFUCULTY . PPD IS DIALYSABLE AND HD WAS REPORTED TO BE
MORE EFFICIENT OVER PERITONEAL DIALYSIS . RENAL LESION REPORTED ARE ACUTE TUBU-
LAR NECROSIS , ACUTE INTERSTITIAL NEPHRITIS AND MESANGIAL PROLIFERATION IN SOME
REPORTS
Suggested Reading:
1) HAIR DYE POISONING IN BUNDELKHAND REGION - JAPI 2011, VOL 59 415-419
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