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ABSTRACTS from 16th International COnference on ... - CRRT Online

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<str<strong>on</strong>g>ABSTRACTS</str<strong>on</strong>g> FROM 17 TH INTERNATIONAL CONFERENCE ON <strong>CRRT</strong>,<br />

SAN DIEGO, FEB 14-17, 2012<br />

and 75 %s were Malays followed by 16<br />

%s Chinese and 9 %s Indians. Twelve<br />

%s had c<strong>on</strong>current cor<strong>on</strong>ary heart<br />

disease, more than half had hypertensi<strong>on</strong><br />

and 48 %s had diabetes. 53.3 % were<br />

referred <str<strong>on</strong>g>from</str<strong>on</strong>g> intensive wards with preand<br />

intra-renal AKI noted in 21.3 and<br />

73.3 %s respectively. Sepsis was<br />

diagnosed in 78.7 % and the pathogens<br />

were identified in 42.3 % of them. At the<br />

start of dialysis, the urea and creatinine<br />

were 3.4 (IQR 2.3) mmol/L and 474<br />

(IQR 398) mcmol/L respectively.<br />

Metabolic acidosis was noted in 76 %<br />

and oliguria in 38.7 %. At least 85.3 %<br />

required dialysis and c<strong>on</strong>venti<strong>on</strong>al HD<br />

was the most comm<strong>on</strong>ly prescribed<br />

while 22.7 % of the patients were started<br />

<strong>on</strong> <strong>CRRT</strong>. The 3-days mortality rate was<br />

28 % and durati<strong>on</strong> of ward stay was 11.5<br />

(IQR 7) days. Patients referred <str<strong>on</strong>g>from</str<strong>on</strong>g> the<br />

intensive wards had higher mortality rate<br />

(37.5 versus 17.1 %s). They were also<br />

frequently started <strong>on</strong> dialysis (39 versus<br />

25 cases, p=.1). Of those treated with<br />

dialysis, 68.8 %s survived and complete<br />

renal recovery was noted in 31.3 %s of<br />

them. Seventeen patients had partial<br />

recovery and seven were dialysisdependent.<br />

<strong>CRRT</strong> had associated with<br />

shorter hospital stay (1 versus 3 days, p=<br />

.4) but not with better clinical outcomes.<br />

C<strong>on</strong>clusi<strong>on</strong>: The overall 3-days<br />

mortality rate was 28 %s and higher in<br />

the intensive wards. Referral <str<strong>on</strong>g>from</str<strong>on</strong>g><br />

intensive wards was the <strong>on</strong>ly factor<br />

associated with poor clinical outcomes<br />

and <strong>CRRT</strong> was not associated with an<br />

improved prognosis in our AKI patients.<br />

Intensive<br />

Wards<br />

General<br />

Wards<br />

n (%) 4 (53.3) 35 (46.7) -<br />

Age<br />

57.5 (IQR<br />

25)<br />

54 (IQR<br />

21)<br />

Gender (M:F) 26:14 21:14<br />

Ethnicity (M:C :I) 31:7:2 25:5:5<br />

Co-morbid<br />

p<br />

value<br />

NS<br />

Diabetes 19 17 NS<br />

Hypertensi<strong>on</strong> 22 18 NS<br />

CAD 5 4 NS<br />

Etiology<br />

Pre-renal (n, %) 6(15) 1 (28.6) NS<br />

Intra-renal (n, %) 34(85) 21 (6) .2<br />

Post-renal (n, %) () 4 (11.4) .3<br />

Sepsis 35 (87.5) 24 (68.) .5<br />

Urea<br />

Creatinine<br />

Potassium<br />

Hemoglobin<br />

White Cell<br />

Platelet<br />

Albumin<br />

3.8 (IQR<br />

19)<br />

46 (IQR<br />

168.5)<br />

5 (IQR<br />

1.6)<br />

1.5 (IQR<br />

3.5)<br />

15.3 (IQR<br />

1.8)<br />

22 (IQR<br />

159)<br />

27 (IQR<br />

8.4)<br />

29 (IQR<br />

22)<br />

56.5 (IQR<br />

49)<br />

4.2 (IQR<br />

1.4)<br />

9.5 (IQR<br />

3.1)<br />

12.3 (IQR<br />

9.8)<br />

223.5<br />

(IQR<br />

143.5)<br />

26.6 (IQR<br />

1.8)<br />

NS<br />

NS<br />

NS<br />

NS<br />

NS<br />

NS<br />

NS<br />

Acidosis 33 24 NS<br />

Coagulopathy 18 11 NS<br />

AKI 1 1 7 NS<br />

AKI 2 2 NS<br />

AKI 3 39 26 .3<br />

Dialysis; Yes 39 25 .1<br />

<strong>CRRT</strong> 16 < .1<br />

LOS<br />

13 (IQR 1) 1 (IQR 8) NS<br />

Mortality 15 (37.5) 6 (17.1) .5<br />

123

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