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Medical Hydrology and Balneology: Environmental Aspects

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<strong>Medical</strong> <strong>Hydrology</strong> <strong>and</strong> <strong>Balneology</strong>: <strong>Environmental</strong> <strong>Aspects</strong><br />

chondrocytes cultivated in DW-DMEM controls. The localitation iNOS, the percentage<br />

of apoptosis <strong>and</strong> necrosis <strong>and</strong> the morphological findings obtained by TEM<br />

confirmed biochemical data.<br />

Conclusions<br />

In conclusion, this in vitro study demonstrates that the water ”Debole di<br />

Vetriolo” counteracts the IL-1-beta induced effects in human OA chondrocyte<br />

cultures. Our data seem to suggest a protective role of this water in cartilage metabolism.<br />

Keywords: Chondrocyte, Interleukin 1 beta, \"Debole di Vetriolo\" Water, Osteoarthritis<br />

188<br />

Balnea<br />

2012, núm. 6, 187-188

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