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revised final - Agency for Toxic Substances and Disease Registry ...

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MERCURY 284<br />

2. HEALTH EFFECTS<br />

The intraperitoneal administration of mercuric chloride at levels comparable to those described above did not<br />

induce a clastogenic response in the spermatogonia of the same mouse strain (Poma et al. 1981). Structural<br />

chromosome aberrations were not produced in metaphase II oocytes of 15 virgin Syrian hamsters receiving a<br />

single intraperitoneal injection of 7.4 mg Hg/kg as methylmercury chloride (Mailhes 1983). However, the<br />

frequency of hyperploid cells in the treated animals was significantly (p

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