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Appendix D Food Codes for NHANES - OEHHA

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Scientific Review PanelSRP Draft Version 2 February,June 2012<br />

and can serve as a useful surrogate <strong>for</strong> PAHs with cancer potency factors<br />

because of their physical-chemical similarity to PAHs with cancer potency<br />

factors.<br />

Less than 30 specific PAHs are measured consistently in biological samples or in<br />

exposure studies. For example, Table J.3-1 lists commonly detectable PAHs in<br />

food and the environment (Phillips, 1999). In one analysis, pyrene and<br />

fluoranthene together accounted <strong>for</strong> half of the measured PAH levels in the diet<br />

(Phillips, 1999). Table J.3-1 includes nine PAHs that have cancer potency factors<br />

and are recognized by <strong>OEHHA</strong> as presenting a carcinogenic risk to humans<br />

(<strong>OEHHA</strong>, 2009).<br />

Table J.3-1: PAHs with and without Cancer Potency Factors Commonly<br />

Measured in <strong>Food</strong> (Phillips, 1999)<br />

PAHs with Cancer Potency<br />

PAHs without Cancer Potency Factors<br />

Factors<br />

Benzo[ghi]perylene Dibenz[a,h]anthracene<br />

Fluoranthene Indeno[1,2,3-cd]pyrene<br />

Pyrene Benzo[a]pyrene<br />

Phenanthrene Benzo[k]fluoranthene<br />

Anthracene Chrysene<br />

Fluorene Benzo[b]fluoranthene<br />

Acenaphthylene Benz[a]anthracene<br />

Acenaphthene Naphthalene<br />

Benzo[b]naphtho[2,1-d]thiophene Benzo[ j]fluoranthene<br />

Benzo[ghi]fluoranthene<br />

Cyclopenta[cd]pyrene<br />

Triphenylene<br />

Perylene<br />

Benzo[e]pyrene<br />

Dibenz[a,j]anthracene<br />

Anthanthrene<br />

Coronene<br />

Few investigators have attempted to correlate PAH exposure from contaminated<br />

food and ambient air with PAH concentrations in human biological samples such<br />

as the blood or mother’s milk. This is likely due to insensitive limits of detection<br />

<strong>for</strong> PAHs yielding few positive measurements, possibly due to the rapid and<br />

extensive metabolism of PAHs in mammals (West and Horton, 1976; Hecht et<br />

al., 1979; Bowes and Renwick, 1986).<br />

This extensive metabolism often results in low or immeasurable concentrations of<br />

PAHs in mother’s milk and blood (e.g. (Kim et al., 2008)). Nevertheless,<br />

emissions of PAHs from stationary sources are common and the increased<br />

J-19

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