Appendix D Food Codes for NHANES - OEHHA

More documents

Recommendations

Info

Scientific Review PanelSRP Draft Version 2 February,June 2012 J.3.1 Inhalation Biotransfer of PAHs to Mother’s Milk Biotransfer of PAHs to breast milk via the mother’s inhalation pathway must be considered separately from biotransfer of PAHs to breast milk from the mother’s oral route. PAHs will show a different pattern of metabolism depending on the route of exposure because of first pass metabolism in the liver from oral exposure, different rates and patterns of metabolism in the lung, and other factors. Smoking cigarettes represents a significant source of PAHs resulting in measurable levels of PAHs in mother’s milk. Therefore, OEHHA chose a study that measured PAH concentrations in breast milk in smoking women and nonsmoking women to estimate inhalation Tcos for PAHs. Of the four studies listed in Table J.3-2, the Italian study by Zanieri et al. (2007) allowed correlation of PAH intake via chronic smoking with PAH levels found in human milk (Zanieri et al., 2007). These investigators reported individual PAH concentrations in the milk of urban smoking and nonsmoking mothers, and in rural smoking and nonsmoking mothers. Zanieri et al (2007) had obtained self-reported smoking habits (an arithmetic average of 5.4 cigarettes smoked per day) but not the daily dose of PAHs due to smoking (Zanieri et al., 2007). Therefore, OEHHA estimated daily PAH doses using published estimates of the amounts of PAHs a smoker voluntarily consumes during smoking per cigarette from simulated cigarette smoking studies. (Ding et al., 2005) measured the amount of 14 individual PAHs that would be inhaled because of smoking major U.S. cigarette brands (Table J.3-3). Two other simulated smoking studies were included that estimated the inhaled amounts of two additional PAHs not covered in the Ding study (Gmeiner et al., 1997; Forehand et al., 2000). J-22
Scientific Review PanelSRP Draft Version 2 February,June 2012 Table J.3-3: Summary Estimates of Polycyclic Aromatic Hydrocarbons (PAHs) Intake from Cigarettes (µg/cigarette) PAH Ding et Ding et Ding et Gmeiner Forehand al (n=5) al al et al et al (n=50) (n=5) (n=3) (n=4) Pooled With Cancer 1 Potency Factors # AM, SD 1 2 3 1 1 AM, SD AM, SD AM, SD AM, SD AM, SD Naphthalene 0.3503, 0.192, 0.407, 0.236, 0.362, 0.292, 0.021 0.044 0.187 0.019 0.011 0.087 Chrysene 0.0157, 0.0197, 0.0314, 0.0218, 0.0112, 0.015, 0.0003 0.0024 0.0028 0.0009 0.0003 0.0017 Benzo[a] 0.0134, 0.0165, 0.0226, 0.0132, 0.014, 0.015, anthracene 0.0007 0.0015 0.0025 0.0005 0.0004 0.0014 Benzo[b] 0.0094, 0.0106, 0.0183, 0.0086, 0.0112, 0.010, fluoranthene 0.003 0.0013 0.0024 0.0003 0.0003 0.0012 Benzo[k] 0.0015, 0.0019, 0.0039, 0.0015, NA 0.0020, fluoranthene 0.00014 0.00029 0.00070 0.00008 0.0004 Benzo[a]pyrene 0.0103, 0.011, 0.0147, 0.0079, 0.0076, 0.0092, 0.00041 0.00077 0.00118 0.00024 0.00023 0.00067 Dibenzo[a,h] NA NA NA 0.0006, 0.0023, 0.0023, anthracene 0.00013 0.00021 0.00017 Indeno[1,2,3-c,d] NA NA NA 0.0035, NA 0.0035, pyrene 0.00039 0.00039 Without Cancer 1 2 3 1 1 Potency Factors AM, SD AM, SD AM, SD AM, SD AM, SD AM, SD Anthracene 0.0749, 0.0698, 0.074, 0.0381, 0.0358, 0.043, 0.0052 0.0084 0.0089 0.0023 0.0011 0.0060 Acenaphthylene 0.1169, 0.0883, 0.153, 0.0504, NA 0.083, 0.0082 0.0097 0.0306 0.0040 0.0167 Phenanthrene 0.1348, 0.1452, 0.144, 0.11, 0.1477, 0.134, 0.0054 0.0131 0.0144 0.0033 0.0044 0.0094 Fluorene 0.2175, 0.1563, 0.257, 0.119, 0.239, 0.184, 0.0087 0.0188 0.0257 0.0048 0.0048 0.0151 Acenaphthene 0.0848, 0.0513, 0.088, 0.0253, NA 0.062, 0.0025 0.0072 0.0167 0.0013 0.0092 Pyrene 0.0486, 0.0495, 0.077, 0.0332, 0.0321, 0.036, 0.0029 0.0069 0.0231 0.0017 0.0010 0.0109 Fluoranthene 0.0744, 0.063, 0.101, 0.0462, 0.0516, 0.056, 0.0037 0.0107 0.0121 0.0018 0.0026 0.0076 Benzo[g,h,i] NA NA NA 0.0025, 0.0023, 0.0023, perylene 0.00030 0.00018 0.00025 1 AM arithmetic mean,, SD standard deviation ; #, Experiment number listed in the study reference by the first author in row one of columns two through six in the table (Gmeiner et al., 1997; Forehand et al., 2000; Ding et al., 2005) J-23
Page 1 and 2:
SRP Review Draft Version 2 June, 20
Page 3 and 4:
Page 5 and 6:
Page 7 and 8:
Page 9 and 10:
Page 11 and 12:
Page 13 and 14:
Page 15 and 16:
Page 17 and 18:
Page 19 and 20:
Page 21 and 22:
Page 23 and 24:
Page 25 and 26:
Page 27 and 28:
Page 29 and 30:
Page 31 and 32:
Page 33 and 34:
Page 35 and 36:
Page 37 and 38:
Page 39 and 40:
Page 41 and 42:
Page 43 and 44:
Page 45 and 46:
Page 47 and 48:
Page 49 and 50:
Page 51 and 52:
Page 53 and 54:
Page 55 and 56:
Page 57 and 58:
Page 59 and 60:
Page 61 and 62:
Page 63 and 64:
Page 65 and 66:
SRPcientific Review Panel Draft Ver
Page 67 and 68:
Page 69 and 70:
Page 71 and 72:
Page 73 and 74:
Page 75 and 76:
Page 77 and 78:
Page 79 and 80:
Page 81 and 82:
Page 83 and 84:
Page 85 and 86:
Scientific Review Panel Draft Febru
Page 87 and 88:
Page 89 and 90:
Page 91 and 92:
Page 93 and 94:
Page 95 and 96:
Page 97 and 98:
Page 99 and 100:
Page 101 and 102:
Page 103 and 104:
Page 105 and 106:
Page 107 and 108:
Page 109 and 110:
Page 111 and 112:
Page 113 and 114:
Page 115 and 116:
Page 117 and 118:
Page 119 and 120:
Page 121 and 122:
Page 123 and 124:
Page 125 and 126:
Page 127 and 128:
Page 129 and 130:
Page 131 and 132:
Page 133 and 134:
Page 135 and 136:
Page 137 and 138:
Page 139 and 140:
Page 141 and 142:
Page 143 and 144:
Page 145 and 146:
Page 147 and 148:
Page 149 and 150:
Page 151 and 152:
Page 153 and 154:
Page 155 and 156:
Page 157 and 158:
Page 159 and 160:
Page 161 and 162:
Page 163 and 164:
Page 165 and 166:
Page 167 and 168:
Page 169 and 170:
Page 171 and 172:
Page 173 and 174:
Page 175 and 176:
Page 177 and 178:
Page 179 and 180:
Page 181 and 182:
Page 183 and 184:
Page 185 and 186:
Page 187 and 188:
Page 189 and 190:
Page 191 and 192:
Page 193 and 194:
Page 195 and 196:
Page 197 and 198:
Page 199 and 200:
Page 201 and 202:
Page 203 and 204:
Page 205 and 206:
Page 207 and 208:
Page 209 and 210:
Page 211 and 212:
Page 213 and 214:
Page 215 and 216:
Page 217 and 218:
Page 219 and 220:
Page 221 and 222:
Page 223 and 224:
Page 225 and 226:
Page 227 and 228:
Page 229 and 230:
Page 231 and 232:
Page 233 and 234:
Page 235 and 236:
Page 237 and 238:
Page 239 and 240:
Page 241 and 242:
Page 243 and 244:
Page 245 and 246:
Page 247 and 248:
Page 249 and 250: SRP Review Draft Version 2 June, 20
Page 279 and 280: Scientific Review PanelSRP Draft Ve
Page 299: Scientific Review PanelSRP Draft Ve
show all

Appendix D Food Codes for NHANES - OEHHA

Create successful ePaper yourself

Delete template?

Save as template?