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Appendix D Food Codes for NHANES - OEHHA

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Scientific Review Panel Draft February, 2012<br />

loading, averaged about 1 to 5 mg/cm 2 during typical human activities in wet soil<br />

with a moisture content of 9 to 18%, and usually less than 0.1 mg/cm 2 with<br />

activities in dry soil with a moisture content of 3-4% (Kissel et al., 1998).<br />

During dermal absorption studies, the soil used to measure dermal uptake is<br />

applied to the skin as a "dry" <strong>for</strong>mulation, i.e. the solvent used in the preparation<br />

of the chemical laden soil is allowed to evaporate prior to dermal application.<br />

The uptake of a soil-bound chemical from wet soil is expected to exceed the<br />

uptake from dry soil because of the increased humidity and temperature at the<br />

skin surface (Wester and Maibach, 1983). Such conditions exist <strong>for</strong> human<br />

exposure scenarios that involve high humidity, high temperature, and skin<br />

covering (e.g. gloves and clothing). Some studies are carried out under condition<br />

of occluded skin, and these studies could be used to estimate chemical<br />

absorption from soil when moisture is present.<br />

In addition, the particle size distribution of soil adhering to skin also needs to be<br />

considered in dermal absorption studies. Most recent dermal absorption studies<br />

have sieved soil down to

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