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NUI Galway – UL Alliance First Annual ENGINEERING AND - ARAN ...

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Development of a mixed-mode cohesive zone model for stent and cell<br />

applications<br />

Ó Máirtίn, É. 1,2 1, 2<br />

, McGarry, P.<br />

Department of Mechanical and Biomedical Engineering, National University of Ireland, <strong>Galway</strong>,<br />

e.omairtin1@nuigalway.ie<br />

Abstract<br />

Cohesive zone models have been commonly used to<br />

simulate coating delamination from a substrate and<br />

crack propagation in certain material types [1]. In this<br />

study we develop a path-dependent cohesive zone<br />

model (CZM). The CZM is then applied to two distinct<br />

case studies: (i) mixed-mode cell debonding during<br />

cyclic substrate stretching and (ii) mixed-mode<br />

overclosure of a stent coating during stent deployment.<br />

Unphysical mixed-mode behaviour is computed for<br />

cohesive zone model formulations derived from an<br />

interface potential function.<br />

1. Introduction<br />

In this study we present a potential-based, coupled<br />

cohesive zone formulation which has been used to<br />

describe many mixed-mode delamination processes. We<br />

propose an alternative, path-dependent cohesive zone<br />

model in an effort to simulate physically realistic mixedmode<br />

behaviour at an interface.<br />

2. Materials and Methods<br />

A path-dependent CZM is developed whereby<br />

interface tractions, Ti, are related to interface<br />

separations, Ui, by<br />

2<br />

U <br />

Ti AiU<br />

i exp 1 exp U<br />

where i= 1,2. Subscripts 1 and 2 refer to normal and<br />

tangential directions respectively. The constants Ai<br />

define the independent interface strengths in the 1 and 2<br />

directions.<br />

Simulations are also performed using a potentialbased<br />

cohesive zone model whereby tractions are<br />

derived from an interface potential function [2],<br />

ø(U1,U2):<br />

i<br />

This requires the definition of n and t; the work of<br />

normal and tangential interface separation, respectively.<br />

Cohesive zone formulations are implemented by means<br />

of UINTER user-defined subroutine in Abaqus ©<br />

Ti U1<br />

U 2 U<br />

software.<br />

, <br />

3. Results<br />

Repulsive normal tractions develop during mixedmode<br />

cell separation following application of potentialbased<br />

model. The cell is forced away from the substrate<br />

at 0% substrate strain, preventing the formation of new<br />

bonds (Figure1(a)).<br />

2<br />

69<br />

Repulsive normal<br />

forces<br />

(a)<br />

Application of the path-dependent model produces a<br />

more realistic result where bond formation occurs at the<br />

end of each strain cycle (Figure1(b)).<br />

(a)<br />

1<br />

0.5<br />

0<br />

-0.5<br />

0 1 2 3 4 5<br />

Time (seconds)<br />

Figure 1. Normal traction and separation results<br />

following application of (a) potential-based CZM and<br />

(b) path-dependent CZM at the cell-substrate interface<br />

(b)<br />

Application of the potential-based model produces<br />

unrealistic coating overclosure and no coating buckling<br />

occurs (Figure2(a)). Overclosure is prevented when<br />

path-dependent model is used with significant buckling.<br />

4. Discussion<br />

Unrealistic repulsive tractions are computed for<br />

mixed-mode cell separation when a potential-based<br />

cohesive zone model is applied at a cell-substrate<br />

interface.<br />

Unrealistic mixed-mode coating overclosure is<br />

computed when a potential-based model is applied at a<br />

stent-coating interface. Implementation of a pathdependent<br />

model leads to more physically realistic<br />

mixed-mode behaviour.<br />

8. References<br />

[1] Y. Yan, F. Shang, “Cohesive zone modeling of interfacial<br />

delamination in PZT thin films”, Int.J.Solids Struct,<br />

Publisher, Location, 2009, 46(13), pp. 2739-2749.<br />

[2] X. P.. Xu, A. Needleman, “Void nucleation by inclusion<br />

debonding in a crystal matrix”, Modell. Simul. Mater. Sci.<br />

Eng, 1994, 1(2), pp.111-132.<br />

(b)<br />

-1<br />

0 1 2 3 4 5<br />

Time (seconds)<br />

Figure 2. Coating deformation after application of<br />

(a) potential-based model and (b) path dependent<br />

model at the stent-coating interface<br />

1<br />

0.5<br />

0<br />

-0.5

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