Handbook of Vitamin C Research

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84Yasuo Kagawa, Shizu Higasa, Masaru Tsujimura et al.supplementation on biochemical and ultrastructural indices of muscle damage after a 21km run. Int. J. Sports Med., 23, 10-15.[74] Gomez-Cabrera, M.C., Domenech, E., Romagnoli, M., Arduini, A., Borras, C.,Pallardo, F.V., Sastre, J. & Vina, J. (2008). Oral administration of vitamin C decreasesmuscle mitochondrial biogenesis and hampers training-induced adaptations inendurance performance. Am. J. Clin. Nutr., 87, 142-149.[75] Duconge, J., Miranda-Massari, J.R., Gonzalez, M.J., Jackson, J.A., Warnock ,W. &Riordan, N.H. (2008). Pharmacokinetics of vitamin C: insights into the oral andintravenous administration of ascorbate. P. R. Health Sci. J., 27, 7-19.[76] Rose, R.C. (1987). Solubility properties of reduced and oxidized ascorbate asdeterminants of membrane permeation. Biochim. Biophys. Acta., 924, 254-256.[77] Kagawa, Y. (1972). Reconstitution of oxidative phosphorylation. Biochim. Biophys.Acta., 265, 297-338.[78] Bates, C.J., Jones, K.S. & Bluck, L.J. (2005). Stable isotope-labelled vitamin C as aprobe for vitamin C absorption by human subjects. Br. J. Nutr., 91, 699-705.[79] Chen, B., Hu, Y., Jin, T., Lu, D., Shao, M., Zheng, L., Wang, Q., Shen, Y., Liu, H.,Liu, Y. & Zhou, Y. (2007). The influence of metabolic gene polymorphisms on urinary1-hydroxypyrene concentrations in Chinese coke oven workers. Sci. Total Environ.,381, 38-46.[80] Chakraborty, D., Bhattacharyya, A., Majumdar, K., Chatterjee, K., Chatterjee, S., Sen,A. & Chatterjee, G.C. (1978). Studies on L-ascorbic acid metabolism in rats underchronic toxicity due to organophosphorus insecticides: effects of supplementation of L-ascorbic acid in high doses. J. Nutr., 108, 973-980.[81] Lykkesfeldt, J., Loft, S., Nielsen, J.B. & Poulsen, H.E. (1997). Ascorbic acid anddehydroascorbic acid as biomarkers of oxidative stress caused by smoking. Am. J. Clin.Nutr., 65, 959-963.[82] Kondo, Y., Sasaki, T., Sato, Y., Amano, A., Aizawa, S., Iwama, M., Handa, S.,Shimada, N., Fukuda, M., Akita, M., Lee, J., Jeong, K.S., Maruyama, N., Ishigami, A.(2008). Vitamin C depletion increases superoxide generation in brains of SMP30/GNLknockout mice. Biochem. Biophys. Res. Commun. 377, 291-296.[83] Wu, X.W., Muzny, D.M., Lee, C.C. & Caskey, C.T. (1992). Two independentmutational events in the loss of urate oxidase during hominoid evolution. J. Mol. Evol.,34, 78-84.[84] Yan, J., Jiao ,Y., Li, X., Jiao, F., Beamer, W.G., Rosen, C.J. & Gu, W. (2007).Evaluation of gene expression profiling in a mouse model of L-gulonolactone oxidasegene deficiency. Genet. Mol. Biol., 30, 322-329.[85] Li, Y., Shi, C.X., Rosenfeld, J., Mossman, K.L., Boo, Y.C. & Schellhorn, H.E. (2008).Restoration of vitamin C synthesis in transgenic Gulo-/- mice by helper-dependentadenoviral-based expression of gulonolactone oxidase. Hum. Gene. Ther., In press.[86] Duffy, S.J., Gokce, N., Holbrook, M., Huang, A., Frei, B., Keaney, J.F. Jr. & Vita, J.A.(1999). Treatment of hypertension with ascorbic acid. Lancet., 354, 2048-2049.[87] Feig, D.I., Kang, D.H., Nakagawa, T., Mazzali, M. & Johnson, R.J. (2006). Uric acidand hypertension. Curr. Hypertens., Rep., 8, 111-115.
Human Specific Vitamin C Metabolism… 85[88] Urso, M.L. & Clarkson, P.M. (2003) Oxidative stress, exercise, and antioxidantsupplementation. Toxicology, 189, 41-54.
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ContentsPrefaceChapter IChapter IIC
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PrefaceThe 6-carbon lactone known a
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Prefaceixbalance of antioxidant and
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Prefacexiprovided or is contradicto
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PrefacexiiiChapter IX - Background:
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Prefacexvdetoxification defence sys
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Prefacexviiprogressed faster than i
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2Kelsey H. Fisher-Wellman and Richa
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10Kelsey H. Fisher-Wellman and Rich
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Vitamin C: Dietary Requirements, Di
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Pro-Oxidant vs. Antioxidant Effects
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Patient. B.H. (38), atopic eczema.V
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186Magdalena Stevanović and Dragan
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In: Handbook of Vitamin C Research
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Molecular Bases of the Cellular Han
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Vitamin C: Daily Requirements, Diet
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262Alan M. Preston, Luis Vázquez Q
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Percent of Study Group Selecting Di
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The Role of Vitamin C in Human Repr
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300Mustafa NazıroğluKeywords: Vit
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302Mustafa NazıroğluNO is synthes
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304Mustafa Nazıroğlu‗recycling
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306Mustafa Nazıroğluagents, such
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308Mustafa NazıroğluFuture Direct
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310Mustafa Nazıroğlu[21] Basu, TK
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312Mustafa Nazıroğlu[59] Cengiz M
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314Samar Al Sayegh Petkovšek and B
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(mgg -1 )320Samar Al Sayegh Petkov
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330Antonio J. López-Farré, José
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Vitamin C in the Treatment of Endot
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Vitamin C Intake by Japanese Patien
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Reciprocal Effects of Ascorbate on
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378Akihito Ishigamicontrols (12,13)
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380Akihito IshigamiFigure 3. Vitami
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382Akihito IshigamiFuture of the SM
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The Importance of Food Processing o
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IndexAA , 249abdominal cramps, 243a
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Index 391atherosclerotic plaque, 23
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Index 393catalase, 6, 13, 169, 181,
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Index 395cyclooxygenase-2, 337, 341
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Index 397endometrium, 286, 294endon
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Index 399GCS, 18gel, x, 87, 92, 121
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Index 401hyperglycaemia, 223hypergl
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Index 403kinetics, 71, 120, 124, 14
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Index 405metastases, 182metastasis,
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Index 407nitrate, 14, 88, 179, 234,
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Index 409phosphodiesterase, 344, 35
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Index 411recovery, vii, 1, 5, 7, 8,
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Index 413steady state, 63, 76, 78st
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Index 415UV, 156, 191, 201, 204, 22
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