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<strong>Vitamin</strong> C: Daily Requirements, Dietary Sources and Adverse Effects 257[54] Solzbach, U., Hornig, B., Jeserich, M., et al. (1997). <strong>Vitamin</strong> C improves endothelialdysfunction <strong>of</strong> epicardial coronary arteries in hypertensive patients. Circulation, 96,1513-1519.[55] Hornig, B., Arakawa, N., Kohler, C., et al. (1998). <strong>Vitamin</strong> C improves endothelialfunction <strong>of</strong> conduit arteries in patients with chronic heart failure. Circulation, 97, 363-368.[56] Higdon, J. An evidence-based approach to vitamins and Minerals. New York: Thieme;65-72, 2003.[57] USDA Nutrient Database for Standard Reference, Release 21 [Online], U.S.Department <strong>of</strong> Agriculture, Agricultural <strong>Research</strong> Service. http://www.nal.usda.gov/fnic/foodcomp [Access February 10, 2009].[58] Barness, L. A. (1974). Safety consideration with high ascorbic acid dosage. Ann N YAcad Sci. 258, 253-258.[59] González, M. J., Mora, E., Riordan, N. H., Riordan, H. D. & Mojica, P. (1998).Rethinking vitamin C and cancer: an update on nutritional oncology. Cancer Prev Int.3, 215-224.[60] Yamamoto, K., Takahashi, M. & Niki, E. (1987). Role <strong>of</strong> iron and ascorbic acid in theoxidation <strong>of</strong> methyl linoleate micelles. Chem Lett. 1, 49-52.[61] Bram, S., Froussard, P., Guichard, M., et al. (1980). <strong>Vitamin</strong> C preferential toxicity formalignant melanoma cells. Nature. 284, 629-631.[62] Tsao, C. S., Dunhan, W. B. & Leung, P. Y. (1989). Effect <strong>of</strong> ascorbic acid and itsderivatives on the growth <strong>of</strong> human mammary tumor xenografts in mice. Cancer J. 5,53-59.[63] Shklar, G., Schwartz, J., Trickler, D. & Cheverie, S. R. (1993). The effectiveness <strong>of</strong> amixture <strong>of</strong> beta carotene, alpha tocopherol, glutathione and ascorbic acid for cancerprevention. Nutr Cancer. 20, 145-151.[64] Cohen, M. & Bhagavan, H. N. (1995). Ascorbic acid and gastrointestinal cancer. J AmColl Nutr. 14, 565-578.[65] Carr, A. & Frei, B. (1999). Does vitamin C act as a pro-oxidant under physiologicalconditions? FASEB 13, 1007-1024.[66] Halliwell, B. & Gutteridge, J. M. C. (1986). Oxygen free radicals and iron in relation tobiology and medicine: some problems and concepts. Free Radical Biol Med, 246, 501-514.[67] Podmore, I. D., Griffiths, H. R., Herbert, K. E., Mistry, N., Mistry, P. & Lunec, J.(1998). <strong>Vitamin</strong> C exhibits pro-oxidant properties. Nature 392, 559.[68] Hininger, I., Waters, R., Osman, M., Garrel, C., Fernholz, K., Roussel, A. M. &Anderson, R. A. (2005). Acute prooxidant effects <strong>of</strong> vitamin C in EDTA chelationtherapy and long-term antioxidant benefits <strong>of</strong> therapy. Free Radical Biol Med, 38,1565-1570.[69] Guidarelli, A., de Sanctis, R., Cellini, B., Fiorani, M., Dacha, M. & Cantoni, O. (2001).Intracellular ascorbic acid enchances the DNA single-strand breakage and toxicityinduced by peroxynitrite in U937 cells. Biochem J, 356, 509-513.[70] Yen, G-C., Duh, P-D. & Tsai, H-L. (2002). Antioxidant and pro-oxidant properties <strong>of</strong>ascorbic acid and gallic acid. Food Chem, 79, 307-313.
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186Magdalena Stevanović and Dragan
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188Magdalena Stevanović and Dragan
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190Magdalena Stevanović and Dragan
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192Magdalena Stevanović and Dragan
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194Magdalena Stevanović and Dragan
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196Magdalena Stevanović and Dragan
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198Magdalena Stevanović and Dragan
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200Magdalena Stevanović and Dragan
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202Magdalena Stevanović and Dragan
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204Magdalena Stevanović and Dragan
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- Page 282 and 283: 262Alan M. Preston, Luis Vázquez Q
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306Mustafa Nazıroğluagents, such
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308Mustafa NazıroğluFuture Direct
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310Mustafa Nazıroğlu[21] Basu, TK
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312Mustafa Nazıroğlu[59] Cengiz M
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314Samar Al Sayegh Petkovšek and B
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316Samar Al Sayegh Petkovšek and B
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318Samar Al Sayegh Petkovšek and B
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(mgg -1 )320Samar Al Sayegh Petkov
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322Samar Al Sayegh Petkovšek and B
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324Samar Al Sayegh Petkovšek and B
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326Samar Al Sayegh Petkovšek and B
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328Samar Al Sayegh Petkovšek and B
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330Antonio J. López-Farré, José
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332Antonio J. López-Farré, José
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334Antonio J. López-Farré, José
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336Antonio J. López-Farré, José
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338Antonio J. López-Farré, José
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340Antonio J. López-Farré, José
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Vitamin C in the Treatment of Endot
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Vitamin C in the Treatment of Endot
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Vitamin C in the Treatment of Endot
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In: Handbook of Vitamin C Research
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Vitamin C Intake by Japanese Patien
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Vitamin C Intake by Japanese Patien
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Vitamin C Intake by Japanese Patien
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In: Handbook of Vitamin C Research
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Reciprocal Effects of Ascorbate on
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Reciprocal Effects of Ascorbate on
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Reciprocal Effects of Ascorbate on
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378Akihito Ishigamicontrols (12,13)
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380Akihito IshigamiFigure 3. Vitami
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382Akihito IshigamiFuture of the SM
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In: Handbook of Vitamin C Research
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The Importance of Food Processing o
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IndexAA , 249abdominal cramps, 243a
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Index 391atherosclerotic plaque, 23
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Index 393catalase, 6, 13, 169, 181,
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Index 395cyclooxygenase-2, 337, 341
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Index 397endometrium, 286, 294endon
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Index 399GCS, 18gel, x, 87, 92, 121
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Index 401hyperglycaemia, 223hypergl
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Index 403kinetics, 71, 120, 124, 14
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Index 405metastases, 182metastasis,
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Index 407nitrate, 14, 88, 179, 234,
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Index 409phosphodiesterase, 344, 35
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Index 411recovery, vii, 1, 5, 7, 8,
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Index 413steady state, 63, 76, 78st
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Index 415UV, 156, 191, 201, 204, 22