Handbook of Vitamin C Research

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124Ana I. Haza, Almudena García and Paloma Morales[96] Qi, W., Russel, J.R., Dun-Xian, T., Joaquin, J.G., Lucien, C.M., Malgorzata, K. &Juan, R.C. (2000). Chromiium(III)-induced 8-hydroxydeoxyguanosine in DNA and itsreduction by antioxidants: comparative effects of melatonin, ascorbate, and vitamin E.Environmental Health Perspectives, 108, 399–402.[97] Cheng, T.J., Kao, H.P., Chan, C.C. & Chang, W.P. (2003). Effects of ozone on DNAsingle-strand breaks and 8-oxoguanine formation in A549 cells. EnvironmentalResearch, 93, 279–284.[98] Rovichová, S., Slamenová, D., Chalupa, I. & Sebová, L. (2004). DNA lesions andcytogenetic changes induced by N-nitrosomorpholine in HepG2, V79 and VH10 cells:the protective effects of vitamins A, C and E. Mutation Research, 560, 91–99.[99] Uhal, BD. (1997). Cell cycle kinetics in the alveolar epithelium. The American Journalof Physiology (Lung Cellular and Molecular Physiology), 272, 1031-1045.[100] Green, D.R. & Reed, J.C. (1998). Mitochondria and apoptosis. Science, 281, 1309-1312.[101] Rich, T., Allen, R.L. & Wyllie, A.H. (2000). Defying death after DNA damage.Nature,407, 777-783.[102] Landvik, N.E., Gorria, M., Arlt, V.M., Asare, N., Solhaug, A., Lagadic- Gossmann, D.& Holme, J.A. (2007). Effects of nitrated-polycyclic aromatic hydrocarbons and dieselexhaust particle extracts on cell signaling related to apoptosis: Possible implications fortheir mutagenic and carcinogenic effects. Toxicology, 231, 159-174.[103] Gosslau, A. & Chen, K.Y. (2004). Nutraceuticals, apoptosis, and disease prevention.Nutrition, 20, 95-102.[104] Blasiak, J., Trzeciak, A., Dziki, A., Ulanska, J. & Pander, B. (2000). Synergestic effectof vitamin C on DNA damage induced by cadmium. General Physiology andBiophysics, 19, 373-379.[105] Bhat, S.H., Azmi, A.S., Hanif, S. & Hadi, S.M. (2006). Ascorbic acid mobilizesendogenous copper in human peripheral lymphocytes leading to oxidative DNAbreakage: a putative mechanism for anticancer properties. The International Journal ofBiochemistry & Cell Biology, 38, 2074-2081.[106] Bram, S., Froussard, P. & Guichard, M. (1980). Ascorbic acid preferential toxicity formalignant melanoma cells. Nature, 284, 629- 631.[107] Park, S., Han, S.S., Park, C.H., Hahm, E.R., Lee, S.J., Park, H.K., Lee, S.H., Kim,W.S., Jung, C.W., Park, K., Riordan, H.D., Kimler, B.F., Kim, K. & Lee, J.H. (2004).L-Ascorbic acid induces apoptosis in acute myeloid leukemia cells via hydrogenperoxide-mediated mechanisms. The International Journal of Biochemistry & CellBiology, 36, 2180-2195.[108] Karasavvas, N., Cárcamo, J.M., Stratis, G. & Golde, D.W. (2005). Vitamin C protectsHL60 and U266 cells from arsenic toxicity. Blood, 105, 4004-4012.[109] Wenzel, U., Nickel, A., Kuntz, S. & Daniel, H. (2004). Ascorbic acid suppresses druginducedapoptosis in human colon cancer cells by scavenging mitochondrial superoxideanions. Carcinogenesis, 25, 703-712.
Vitamin C Protects from Oxidative DNA Damage… 125[110] Perez-Cruz, I., Cárcamo, J.M. & Golde, D.W. (2003). Vitamin C inhibits FAS-inducedapoptosis in monocytes and U937 cells. Blood, 102, 336-343.[111] Dhar-Mascareño, M., Cárcamo, J.M. & Golde, D.W. (2005). Hypoxia-reoxygenationinducedmitochondrial damage and apoptosis in human endothelial cells are inhibitedby vitamin C. Free Radical Biology & Medicine, 38, 1311-1322.
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ContentsPrefaceChapter IChapter IIC
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PrefaceThe 6-carbon lactone known a
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Prefaceixbalance of antioxidant and
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Prefacexiprovided or is contradicto
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PrefacexiiiChapter IX - Background:
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Prefacexvdetoxification defence sys
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Prefacexviiprogressed faster than i
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2Kelsey H. Fisher-Wellman and Richa
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10Kelsey H. Fisher-Wellman and Rich
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In: Handbook of Vitamin C Research
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Human Specific Vitamin C Metabolism
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mgmgmgHuman Specific Vitamin C Meta
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Page 149 and 150: Vitamin C: Dietary Requirements, Di
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Pro-Oxidant vs. Antioxidant Effects
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186Magdalena Stevanović and Dragan
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Molecular Bases of the Cellular Han
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Vitamin C: Daily Requirements, Diet
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262Alan M. Preston, Luis Vázquez Q
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Percent of Study Group Selecting Di
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The Role of Vitamin C in Human Repr
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300Mustafa NazıroğluKeywords: Vit
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302Mustafa NazıroğluNO is synthes
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304Mustafa Nazıroğlu‗recycling
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306Mustafa Nazıroğluagents, such
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308Mustafa NazıroğluFuture Direct
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310Mustafa Nazıroğlu[21] Basu, TK
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312Mustafa Nazıroğlu[59] Cengiz M
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314Samar Al Sayegh Petkovšek and B
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(mgg -1 )320Samar Al Sayegh Petkov
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330Antonio J. López-Farré, José
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Vitamin C in the Treatment of Endot
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Vitamin C Intake by Japanese Patien
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Reciprocal Effects of Ascorbate on
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378Akihito Ishigamicontrols (12,13)
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380Akihito IshigamiFigure 3. Vitami
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382Akihito IshigamiFuture of the SM
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The Importance of Food Processing o
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IndexAA , 249abdominal cramps, 243a
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Index 391atherosclerotic plaque, 23
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Index 393catalase, 6, 13, 169, 181,
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Index 395cyclooxygenase-2, 337, 341
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Index 397endometrium, 286, 294endon
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Index 399GCS, 18gel, x, 87, 92, 121
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Index 401hyperglycaemia, 223hypergl
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Index 403kinetics, 71, 120, 124, 14
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Index 405metastases, 182metastasis,
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Index 407nitrate, 14, 88, 179, 234,
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Index 409phosphodiesterase, 344, 35
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Index 411recovery, vii, 1, 5, 7, 8,
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Index 413steady state, 63, 76, 78st
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Index 415UV, 156, 191, 201, 204, 22
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