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Food Lipids: Chemistry, Nutrition, and Biotechnology

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55. C. Ip, S. F. Chin, J. A. Scimeca, <strong>and</strong> M. W. Pariza. Mammary cancer prevention by<br />

conjugated dienoic derivative of linoleic acid. Cancer Res. 51:6118–6124 (1991).<br />

56. C. Ip, S. P. Briggs, A. D. Haegele, H. J. Thompson, J. Storkson, <strong>and</strong> J. A. Scimeca.<br />

The efficacy of conjugated linoleic acid in mammary cancer prevention is independent<br />

of the level or type of fat in the diet. Carcinogenesis 17:1045–1050 (1996).<br />

57. C. Ip, C. Jiang, H. J. Thompson, <strong>and</strong> J. A. Scimeca. Retention of conjugated linoleic<br />

acid in the mammary gl<strong>and</strong> is associated with tumor inhibition during the post-initiation<br />

phase of carcinogenesis. Carcinogenesis 18:755–759 (1997).<br />

58. C. Liew, H. A. Schut, S. F. Chin, M. W. Pariza, <strong>and</strong> R. H. Dashwood. Protection of<br />

conjugated linoleic acids against 2-amino-3-methylimidazo[4,5-f]quinoline-induced colon<br />

carcinogenesis in the F344 rat: A study of inhibitory mechanisms. Carcinogenesis<br />

16:3037–3043 (1995).<br />

59. A. Cesano, S. Visonneau, J. A. Scimeca, D. Kritchevsky, <strong>and</strong> D. Santoli. Opposite<br />

effects of linoleic acid <strong>and</strong> conjugated linoleic acid on human prostatic cancer in SCID<br />

mice. Anticancer Res. 18:1429–1434 (1998).<br />

60. M. M. Ip, P. A. Masso-Welch, S. F. Shoemaker, W. K. Shea-Eaton, <strong>and</strong> C. Ip. Conjugated<br />

linoleic acid inhibits proliferation <strong>and</strong> induces apoptosis of normal rat mammary<br />

epithelial cells in primary culture. Exp. Cell Res. 250:22–34 (1999).<br />

61. D. C. Cunningham, L. Y. Harrison, <strong>and</strong> T. D. Shultz. Proliferative responses of normal<br />

human mammary <strong>and</strong> MCF-7 breast cancer cells to linoleic acid, conjugated linoleic<br />

acid <strong>and</strong> eicosanoid synthesis inhibitors in culture. Anticancer Res. 17:197–203 (1997).<br />

62. S. Banni, E. Angioni, V. Casu, M. P. Melis, G. Carta, F. P. Corongiu, H. Thompson,<br />

<strong>and</strong> C. Ip. Decrease in linoleic acid metabolites as a potential mechanism in cancer<br />

risk reduction by conjugated linoleic acid. Carcinogenesis 20:1019–1024 (1999).<br />

63. K. N. Lee, D. Kritchevsky, <strong>and</strong> M. W. Pariza. Conjugated linoleic acid <strong>and</strong> atherosclerosis<br />

in rabbits. Atherosclerosis 108:19–25 (1994).<br />

64. R. J. Nicolosi, E. J. Rogers, D. Kritchevsky, J. A. Scimeca, <strong>and</strong> P. J. Huth. Dietary<br />

conjugated linoleic acid reduces plasma lipoproteins <strong>and</strong> early aortic atherosclerosis in<br />

hypercholesterolemic hamsters. Artery 22:266–277 (1997).<br />

65. M. E. Cook, C. C. Miller, Y. Park, <strong>and</strong> M. Pariza. Immune modulation by altered<br />

nutrient metabolism: <strong>Nutrition</strong>al control of immune-induced growth depression. Poult.<br />

Sci. 72:1301–1305 (1993).<br />

66. C. C. Miller, Y. Park, M. W. Pariza, <strong>and</strong> M. E. Cook. Feeding conjugated linoleic acid<br />

to animals partially overcomes catabolic responses due to endotoxin injection. Biochem.<br />

Biophys. Res. Commun. 198:1107–1112 (1994).<br />

67. M. Sugano, A. Tsujita, M. Yamasaki, M. Noguchi, <strong>and</strong> K. Yamada. Conjugated linoleic<br />

acid modulates tissue levels of chemical mediators <strong>and</strong> immunoglobulins in rats. <strong>Lipids</strong><br />

33:521–527 (1998).<br />

68. J. J. Turek, Y. Li, I. A. Schoenlein, K. G. D. Allen, <strong>and</strong> B. A. Watkins. Modulation of<br />

macrophage cytokine production by conjugated linoleic acids is influenced by the dietary<br />

n-6:n-3 fatty acid ratio. J. Nutr. Biochem. 9:258–266 (1998).<br />

69. J. P. DeLany, F. Blohm, A. A. Truett, J. A. Scimeca, <strong>and</strong> D. B. West. Conjugated<br />

linoleic acid rapidly reduces body fat content in mice without affecting energy intake.<br />

Am. J. Physiol. 276:R1172-R1179 (1999).<br />

70. M. Yamasaki, K. Mansho, H. Mishima, M. Kasai, M. Sugano, H. Tachibana, <strong>and</strong> K.<br />

Yamada. Dietary effect of conjugated linoleic acid on lipid levels in white adipose<br />

tissue of Sprague–Dawley rats. Biosci. Biotechnol. Biochem. 63:1104–1106 (1999).<br />

71. Y. Park, J. M. Storkson, K. J. Albright, W. Liu, <strong>and</strong> M. W. Pariza. Evidence that the<br />

trans-10,cis-12 isomer of conjugated linoleic acid induces body composition changes<br />

in mice. <strong>Lipids</strong> 34:235–241 (1999).<br />

72. K. L. Houseknecht, J. P. V. Heuvel, S. Y. Moya-Camerena, C. P. Portocarrero, K. P.<br />

Nickel, <strong>and</strong> M. A. Belury. Dietary conjugated linoleic acid normalizes impaired glucose<br />

Copyright 2002 by Marcel Dekker, Inc. All Rights Reserved.

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