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(VCCEP) Tier 1 Pilot Submission for BENZENE - Tera

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Table 7.30: Average of Mean In-Vehicle Concentrations<br />

Chang et al. (2000)<br />

Benzene <strong>VCCEP</strong> <strong>Submission</strong><br />

March 2006<br />

Study Description<br />

Urban, Baltimore in Summer 1998<br />

and Winter 1999<br />

130<br />

Mean In-Vehicle<br />

Concentration<br />

(µg/m 3 )<br />

Batterman et al. (2002) Urban commute, Detroit, fall 1999 4.5<br />

Fedoruk and Kerger (2003)<br />

10.2<br />

Urban communte, Los Angeles ,<br />

1997<br />

2.4<br />

Average of study means 5.7<br />

Due to various driving conditions under which a person may be exposed to in-vehicle<br />

concentrations of benzene, mean concentrations best portray long-term exposure<br />

concentrations. An average concentration was derived using the means of each of the three key<br />

studies above. This average is used as the typical representative in-vehicle exposure<br />

concentration and is considered to be an average of a high-end scenario, as it is representative<br />

of urban exposures where traffic densities are highest.<br />

Age-specific in-vehicle benzene exposures were quantified according to the following equation:<br />

where:<br />

C × ED × EF × ET × IR × ABSi × CF<br />

ADD =<br />

BW × AT<br />

ADD = average daily dose (mg/kg-day)<br />

C = concentration of benzene in vehicle air (µg/m 3 )<br />

ED = exposure duration (years)<br />

EF = exposure frequency (days/year)<br />

ET = exposure time (hours/day)<br />

CF = conversion factor (0.001 mg/µg)<br />

ABSi = benzene inhalation absorption factor; 0.5 (unitless)<br />

IR = inhalation rate (m 3 /hour)<br />

BW = body weight (kg)<br />

AT = averaging time (days)

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