(VCCEP) Tier 1 Pilot Submission for BENZENE - Tera

Table 8.13. Cancer margins of safety associated with benzene exposures
Results of cancer margin of safety analysis for the general population under various exposure scenarios.
Cancer Margin of Safety (unitless)
Female Male
INHALATION PATHWAYS
Outdoor air (ambient, total)
Rural - Typical 8,200 7,800
Rural - High End 5,900 5,600
Urban - Typical 3,700 3,600
Urban - High End
Indoor air (in-home, total)
1,300 1,300
Typical 210 200
High End
In school
45 43
Typical 7,200 7,200
High End 1,500 1,500
In vehicle - typical
Showering
1,400 1,300
Typical 36,000 36,000
High End 1,800 1,800
BACKGROUND
Inhalation Pathway (indoor & outdoor air, showering, in-vehicle)
Rural - Typical 170 160
Rural - High End 41 39
Urban - Typical 170 160
Urban - High End
Ingestion Pathway (food & water)
40 38
Typical 3,800 3,800
High End 300 300
Occupational - Typical a
3,100 3,100
Occupational - High End a
Dermal Pathway (showering)
280 280
Typical 100,000 100,000
High End 35,000 35,000
BACKGROUND (all pathways)
Rural - Typical 160 160
Rural - High End 36 35
Urban - Typical 160 150
Urban - High End 36 34
BACKGROUND (all pathways, including indirect occupational) a
Rural - Typical 160 160
Rural - High End 36 34
Urban - Typical 160 150
Urban - High End 35 34
SOURCE-SPECIFIC DOSES
Tobacco Smoke
ETS (nonsmoker's dose) 550 520
Mainstream (smoker's dose)
Refueling
7.4 7.5
Typical 7,400 6,800
High End
BACKGROUND PLUS REFUELING
610 560
Rural - Typical 160 150
Rural - High End 34 33
Urban - Typical 160 150
Urban - High End 34 32
(footnotes on following page)
Benzene VCCEP Submission
March 2006
191