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Universidad de Córdoba BIODISPONIBILIDAD MINERAL DE ...

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This effect increase can be explained by the fact that the<br />

fructooligosacchari<strong>de</strong>s can not be <strong>de</strong>gra<strong>de</strong>d by the enzymes present in the<br />

small intestine and therefore arrive practically intact to the colon where they are<br />

fermented by the bacterial flora present there, with <strong>de</strong>veloping gases, lactose<br />

and organic acids such as acetate, propionate and butyrate that lower the pH<br />

and make the calcium more soluble (38). These organic acids improve the<br />

absorption of calcium (39-45) in the colon of rats by forming low-charged<br />

mineral complexes (43), thus facilitating the transport by passive diffusion of<br />

these mineral complexes because the cell membranes have low permeability to<br />

highly charged ions like calcium (39). This effect varies according to the<br />

concentrations of calcium and organic acids present in the colon, indicanting a<br />

higher effec to propionate probably because propionate is more lipid soluble<br />

and, therefore, crosses the cell membrane more easily (42, 44).<br />

Another hypothesis to explain the beneficial effect of<br />

fructooligosacchari<strong>de</strong>s as fermentable carbohydrates is the stimulation of<br />

bacterial proliferation in the colon, with a subsequently greater secretion of<br />

phytase, which would enhance the hydrolysis of phytate to phosphate and<br />

inositol (45), preventing the binding of phytate to mineral cations like calcium.<br />

Calcium fortification of foods<br />

The most wi<strong>de</strong>ly used salts for calcium fortification are calcium<br />

glycerophosphate, calcium gluconate and/or calcium lactate. The type of<br />

93

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