Universidad de Córdoba BIODISPONIBILIDAD MINERAL DE ...

Resultados
Table 3.- Effects of phytic acid on iron availability
Study/
Factors
In vitro
Phytate
Effects on iron availability
Strong interaction of phytate with iron at
any pH
References
Notan et al. (1987)
Phytate Inhibition of iron uptake in Caco-2 cells Glahn et al. (2002)
Skoglund et al.
(1999)
White beans
Vegetarian diet
Infant formulas
Low iron dialisability due to proteinmineral-phytate
complexes
Negative correlation between phytic acid
and iron availability (r∼ -0,9)
No effect is observed due to low phytic
acid and high ascorbic acid content
Lombardi-Boccia et
al. (1998)
Pushpanjali &
Khokhar (1996)
Jovaní et al. (2000)
In vivo
(humans)
Vegetarian diet Inadequate for maintaining iron balance Shaw et al. (1995)
Bread
Inbition of iron absorption is closely
related to the content of phytate
Brune et al. (1992)
Phytate-rich meal Addition of small amounts of pork (50
and 75 g) meat increased iron
absorption (44% and 57% respectively)
Baech et al. (2003)
Infant formulas
Infant formulas
Increase in iron absorption after doubling
the concentration of ascorbic acid (from
14,8% to 22,1%)
Iron absorption increased significantly
after the degradation of phytic acid (from
20,7% to 33,1%)
Davidsson et al.
(1994)
Davidsson et al.
(2001)
Davidsson et al.
(2001)
Other studies have found that fructooligossacharides improved recovery
from anemia due to iron deficiency as a consequence of an increase in soluble
iron in the cecal content in rats and consequently an increase in net iron
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