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stiinte med 1 2012.indd - Academia de Ştiinţe a Moldovei

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248<br />

processes and prevention of installation of multiple<br />

organ injuries improving wound healing.<br />

The revealed postoperative results confirm the<br />

efficacy of diagnostically techniques and <strong>med</strong>icosurgical<br />

attitu<strong>de</strong> which <strong>de</strong>monstrated good results in<br />

all100 % of the cases.<br />

References<br />

1. Lebrec D., Hemodynamic effects of endotoxin<br />

and platelet activating factor in cirrhotic rats.<br />

Gastroenterology, 1992; 103:282-288.<br />

2. Van Deventer S.J.H., Ten Cate J.W., Tytgat<br />

G.N.J., Intestinal endotoxemia: clinical signifi cance.<br />

Gastroenterology, 1988; 94: 825-831.<br />

3. Ni R.Y., Hepatogastrointestinal dysfunction. Ni<br />

R.Y., Advanced doctor training course for infectious<br />

diseases. Wuhan:Wuhan University Press, 1996:33-34.<br />

4. Kaufhold A., Behrendt W., Krauss T., Van Saene<br />

H., Selective <strong>de</strong>contamination of the digestive tract and<br />

methicillin-resistant staphylococcus aureus. Lancet, 1992;<br />

339:1411-1412.<br />

5. Blaise M., Pateron D., Trinchet J.C., Levacher S.,<br />

Beaugrand M., Pourriat J.L., Systemic antibiotic therapy<br />

prevents bacterial infection in cirrhotic patients with<br />

gastrointestinal hemorrhage. Hepatology, 1994; 20:34-38.<br />

6. Deitch E.A., Maejima K., Berg R., Effect of oral<br />

antibiotics and bacterial overgrowth on the translocation<br />

of the GI tract microfl ora in burned rats. J Trauma, 1985;<br />

25:385-392.<br />

7. Multiple-organ failure: generalized auto<strong>de</strong>structive<br />

infl ammation? Arch. Surg., 1985; 120:1109-1115.<br />

8. Marshall J.C., Sweeney D., Microbial infection and<br />

the septic response in critical illness. Arch. Surg., 1990;<br />

125:17-23.<br />

9. Bone R.G., Sepsis. SIRS and MODS: the new<br />

<strong>de</strong>fi nition. Proceedings of Sepsis/SIRS. Washington, DC,<br />

February 21-22, 1995.<br />

10. Bohnen J.M.A., Solomkin J.S., Dellinger E.P., et<br />

al. Gui<strong>de</strong>lines for clinical care: anti-infective agents for<br />

intra-abdominal infection: Surgical Infection Society<br />

policy statement. Arch. Surg., 1992; 127:83-89.<br />

11. Wittmann D.H., Symposium of intra-abdominal<br />

infections: introduction. World J. Surg., 1990; 14:145-<br />

230.<br />

12. Wittmann D.H., Walker A.P., Condon R.E.,<br />

Peritonitis, intra-abdominal infection, and intra-abdominal<br />

abscess. Schwartz S.I., Shires G.T., Spencer F.C., eds.<br />

Principles of Surgery. 6th ed. New York: McGraw Hill:<br />

1993:1449-1484.<br />

13. Rotstein O.D., Meakins J.L., Diagnostic and<br />

therapeutic challenges of intra-abdominal infections.<br />

World J. Surg., 1990; 14:159-166.<br />

Rezumat<br />

Articolul prezintă o analiză a rezultatelor obţinute în<br />

tratamentul peritonitei apendiculare acute generalizate,<br />

utilizând tehnici <strong>de</strong> diagnostic special selectate şi tratament<br />

<strong>med</strong>ico-chirurgical.<br />

Buletinul AŞM<br />

Analizând literatura <strong>de</strong> specialitate şi reieşind din<br />

studiile personale, se poate concluziona că tratamentul<br />

chirurgical individualizat este doar o etapă în procesul<br />

terapeutic şi este necesar <strong>de</strong> a reechilibra o multitudine<br />

<strong>de</strong> tulburări biochimice, metabolice, acido-bazice,<br />

consi<strong>de</strong>rate ca fiind şi potenţiali factori <strong>de</strong> risc în instalarea<br />

complicaţiilor septico-purulente, abcese, ocluzii intestinale<br />

la copil.<br />

Summary<br />

The present article present an analysis of the results<br />

in treatment of appendicular acute generalized peritonitis,<br />

using special selected diagnostically methods and <strong>med</strong>icosurgical<br />

treatment.<br />

It can be consi<strong>de</strong>red, analyzing literature of specialty,<br />

that the individualized treatment it is only one step in<br />

therapeutically arsenal and it is necessary to reechilibrate<br />

a multitu<strong>de</strong> of biochemical, metabolic, acido-basic<br />

disturbances consi<strong>de</strong>ring being potential factor of risk in<br />

installation of septico-purulent complications.<br />

Резюме<br />

Статья представляет анализ результатов лечения<br />

острого разлитого перитонита у детей аппендикулярного<br />

генеза с применением специальных методов диагностики<br />

и лечения.<br />

Анализируя литературные данные и собственные<br />

наблюдения на 320 детей, оперированныx в нашей клинике,<br />

можно сделать вывод, что хирургическое лечение<br />

– это только один этап в лечении разлитого перитонита<br />

у детей. Кроме этого, необходимо устранить биохимические,<br />

метаболические и кислотно-щелочные нарушения,<br />

которые являются факторами риска в развитии<br />

таких гнойно-септических осложнений, как абсцессы<br />

брюшной полости, кишечная непроходимость, сепсис<br />

и синдром полиорганной недостаточности.<br />

CONGENITAL LOBAR EMPHYSEMA<br />

IN CHILDREN<br />

_______________________________________<br />

Eva Gudumac, Aca<strong>de</strong>mician SAM, PhD in<br />

<strong>med</strong>icine, univ. professor, Professor emerita,<br />

Alina Danila, doctoral candidate, NSPCPS<br />

„Aca<strong>de</strong>mician Natalia Gheorghiu”<br />

Introduction<br />

Congenital localized emphysema (lobar<br />

emphysema, obstructive emphysema, hypertrophic<br />

emphysema, polialveolar lobe) represents a congenital<br />

terminal (distal) bronchopulmonary malformation<br />

and is <strong>de</strong>fined as a progressive diffuse, abnormal<br />

and uniform hyperinflation of the pulmonary alveoli,<br />

of one or two lobes, usually of the upper one, with<br />

the subsequent formation of one or more bubbles<br />

un<strong>de</strong>r pressure, without a wall of their own, with the

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