Clinical Trials and Preclinical Infrastructure Asset Map - Life Sciences

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BRITISH COLUMBIA
Neonatal Research Program
Neonatology is an area of health care in which decisions can impact dramatically on the future quality
of life of both patients and their families. To support this decision process, research is an integral part of
the daily activities in the Program. A core group of health researchers are involved in individual activities
that combine to create a comprehensive, complementary approach to minimizing the long-term
effects of prematurity. The researchers have demonstrated expertise in: basic science (i.e., inflammation
and oxidants), clinical research (i.e., randomized controlled trials, neonatal brain imaging), health
services research (i.e., ACoRN-community outreach) and population health (i.e., Neonatal Follow-up).
Specific areas of clinical interest are: ventilation and critical care therapy, role of immunity and genetics
in neonatal disease, nutrition, stress/pain, brain development and injury, and long-term neurodevelopment.
The Program offers investigators:
• Protocol, informed consent and budget review
• Assistance with grant preparation/ submission
• REB preparation and submission - including amendments, renewals and requests for acknowledgement
• Set-up of study account and tracking financial expenses of study
• Data collection, management and analysis
• Liaising with pharmacy, laboratory, health records, neonatal intensive care unit (NICU) nursing or
other groups as necessary to help with study initiation
• Hiring and training of research staff
• Review, preparation and submission of abstracts/manuscripts
• Review/Development of sub-site clinical trial agreements
• Access to the opportunity to conduct Phase I, II, III, and IV clinical trials and biomedical research
within the NICU, which admits approximately 700 in-patients per year.
The Program includes 13 Principal Investigators as listed below, and five Affiliated Investigators. Their
details can be found in Appendix 6. Its structure is shown in Figure A5. It has no independent URL.
Principal Investigators
• Chessex, Philippe (Head)
• Albersheim, Susan
• Holsti, Liisa
• Lavoie, Pascal
• Lupton, Brian
• Miller, Steven
• Osiovich, Horacio
• Sherlock, Rebecca
• Singh, Avash
• Smyth, John
• Solimano, Alfonso
• Synnes, Anne
• Whitfield, Michael
The following table shows all the research interests of each investigator in neonatology, not just clinical
trials:
Disease Focus Types of Studies Investigators
Effects of nutrition, oxidants, and antioxidants Animal studies
Chessex, Philippe
on biological markers and clinical outcome Randomized clinical trials
Ethics and decision-making in a vulnerable Qualitative research Albersheim, Susan
population
Stress/pain Clinical research Holsti, Liisa