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Clinical Trials and Preclinical Infrastructure Asset Map - Life Sciences

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86<br />

BRITISH COLUMBIA<br />

Multiple Sclerosis Clinic<br />

The Multiple Sclerosis Clinic (www.ubcneurology.com/Research_MS.html) operates at UBC Hospital.<br />

It had 3,698 patient visits <strong>and</strong> 635 new patients in 2007. The clinic coordinates new escalating therapy<br />

options for aggressive MS <strong>and</strong> also provides specialized care for neuromyelitis optica (NMO). It provides<br />

outreach support to clinics in Victoria (1,000 patients registered), Kelowna (700 patients), <strong>and</strong> Prince<br />

George (300 patients), as well as providing outreach care directly to patients in Comox (Vancouver<br />

Isl<strong>and</strong>).<br />

Therapeutic trials in MS have encompassed both disease modifying <strong>and</strong> symptomatic therapies. All<br />

stages <strong>and</strong> types of MS have been represented in at least Phases II <strong>and</strong> III trials. Investigators have a<br />

strong profile in clinical trial development, safety monitoring <strong>and</strong> MRI/immunology sub-studies. The<br />

MS/MRI Research Group has provided central analysis for numerous international multicentre r<strong>and</strong>omized<br />

clinical trials <strong>and</strong> are recognized internationally for their work in this area.<br />

The Clinic’s seven neurologist investigators are as follows, with details contained in Appendix 6:<br />

• Devonshire, Virginia • Oger, Joel<br />

• Hashimoto, Stanley • Rieckmann, Peter<br />

• Hooge, John<br />

• Traboulsee, Anthony<br />

• Kastrukoff, Lorne<br />

Contact:<br />

Traboulsee, A. Head of <strong>Clinical</strong> <strong>Trials</strong> Group. Tel: 604 822-0788. trabouls@interchange.ubc.ca.<br />

Pacific Parkinson’s Research Centre<br />

Located at UBC Hospital, the Pacific Parkinson’s Research Centre is a multidisciplinary program dedicated<br />

to the diagnosis <strong>and</strong> management of Parkinson’s <strong>and</strong> other related disorders, such as tremor <strong>and</strong><br />

dystonia (www.parkinsons.ubc.ca/index.html). It has been designated as a Centre of Excellence by the<br />

National Parkinson Foundation in the US. In addition to treating patients, it has a strong research program<br />

that spans preclinical, clinical <strong>and</strong> population studies. Under the direction of Dr. Jonathan Stoessl,<br />

an internationally recognized expert on Parkinson’s disease, the centre has the largest peer-reviewed<br />

research program in Canada on Parkinson’s disease.<br />

The Centre has three neurologists (listed below), whose details can be found in Appendix 6.<br />

• McKeown, Martin J.<br />

• Stoessl, Jonathan<br />

• Tsui, Joseph<br />

These investigators conduct trials involving novel drugs, surgery, <strong>and</strong> neuroimaging. Patients registered<br />

with the UBC Movement Disorders Clinic in 2007 included 1,100 with typical Parkinson’s disease, 400<br />

patients with Parkinson-like disorders, <strong>and</strong> 500 – 1,000 with dystonia 5 .<br />

The Centre also has a clinical trials coordinator. It conducts Phases I, II, III, <strong>and</strong> IV studies.<br />

Contact:<br />

Babul, Shamin. Administrator. Tel: 604-822-7721. ndsb@interchange.ubc.ca.

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