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Environmental Problems, Their Causes, and Sustainability 1

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ozone in the stratosphere. From a human st<strong>and</strong>pointthe answer is that with less ozone in the stratosphere,more biologically damaging UV-A <strong>and</strong> UV-B radiationwill reach the earth’s surface. This will give humansworse sunburns, more eye cataracts (a clouding of theeye’s lens that reduces vision <strong>and</strong> can cause blindnessif not corrected), <strong>and</strong> more skin cancers (Figure 21-25<strong>and</strong> Connections, at right).Humans can make cultural adaptations to increasedUV radiation by staying out of the sun, protectingtheir skin with clothing, <strong>and</strong> applying sunscreens.However, plants <strong>and</strong> animals that help support us <strong>and</strong>other forms of life cannot make such changes exceptthrough biological evolution, a process that can take along time.Connections: What Cancer Are You MostLikely to Get? Look in the MirrorExposure to UV radiation is a major cause of skincancers.Research indicates that years of exposure to UV-B ionizingradiation in sunlight is the primary cause of squamouscell (Figure 21-25, left) <strong>and</strong> basal cell (Figure 21-25,center) skin cancers. Together these two types make up95% of all skin cancers. Typically there is a 15- to 40-year lag between excessive exposure to UV-B <strong>and</strong> developmentof these cancers.Caucasian children <strong>and</strong> adolescents who experienceonly one severe sunburn double their chances ofgetting these two types of cancers. Some 90–95% ofThis long-wavelength(low-energy) form of UVradiation causes aging ofthe skin, tanning, <strong>and</strong>sometimes sunburn. Itpenetrates deeply <strong>and</strong>may contribute to skincancer.UltravioletAUltravioletBThis shorter-wavelength (high-energy) formof UV radiation causes sunburn, prematureaging, <strong>and</strong> wrinkling. It is largely responsiblefor basal <strong>and</strong> squamous cell carcinomas<strong>and</strong> plays a role in malignant melanoma.Thin layer ofdead cellsHairSquamouscellsBasallayerMelanocytecellsBasalcellEpidermisSweatgl<strong>and</strong>DermisBloodvesselsSquamous Cell CarcinomaArising from cellsin the upper layerof the epidermis,this cancer is alsocaused by exposureto sunlight or tanninglamps. It is usuallycurable if treated early. It grows faster thanbasal cell carcinoma <strong>and</strong> can metastasize.Basal Cell CarcinomaThe most commonskin malignancyusually is causedby excessiveexposure to sunlightor tanning lamps.It develops slowly,rarely metastasizes <strong>and</strong> is nearly 100%curable if diagnosed early <strong>and</strong> treated properly.MelanomaThis deadliest ofskin cancersinvolves melanocytecells, which producepigment. It c<strong>and</strong>evelop from a moleor on blemishedskin, grows quickly, <strong>and</strong> can spread to otherparts of the body (metastasize).Figure 21-25 Structure of the human skin <strong>and</strong> the relationships between ultraviolet (UV-A <strong>and</strong> UV-B) radiation<strong>and</strong> the three types of skin cancer. (The Skin Cancer Foundation)http://biology.brookscole.com/miller14487

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