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concenrration <strong>of</strong> exhaled NO was 84.8ppb (SEM 14.0, range 25.I - 189.0). <strong>The</strong>re was greater<br />

variation shown in the female subjects with a mean <strong>of</strong> 92.4ppb (SEM 36.9,26.2 - 189.0) than<br />

the male subjecrs with a mean <strong>of</strong> 71.7ppb (SEM 28.7, range 25.1 - 141.0). <strong>The</strong> peak exhaled<br />

NO levels measured through the t-piece system were lower in all the subjects with a total<br />

subject mean <strong>of</strong> 41.2ppb (SEM 10.8, range 10.00 - 101.6). <strong>The</strong> mean in males was 33.2ppb<br />

(SEM 8.4) versus females <strong>of</strong> 50.7ppb (SEM 12.3) (see Figure 6.6). <strong>The</strong> data for one<br />

individual as the change occurred from t-piece to direct measurement is shown in Figure 6.7.<br />

Note again that the chart recording is read from right to left so the exhalation commences at<br />

the right hand side <strong>of</strong> each set <strong>of</strong> tracings. <strong>The</strong> scales were added for convenience <strong>of</strong> viewing<br />

this single tracing as the scales were worked out on each graph depending on the checks with<br />

the calibration gases. <strong>The</strong> main point depicted is the change with higher NO levels being<br />

measured in the direct rather than the t-piece system.<br />

Figure 6.5: Example <strong>of</strong> recording on one subject - direct and t-piece measurements<br />

Note the chart is read from right to left, NO is recorded in green, COz is recorded in red, mouth<br />

pressure is recorded in blue and flow (seen only in the t-piece measurements) is recorded in brown'<br />

<strong>The</strong> exhaled NO levels increase when the tiace moves from t-piece to direct recordings. <strong>The</strong><br />

calculations made for each exhalation can also be seen on the chart.<br />

t4l

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