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3. As a marker to follow when commencing treatment, in essence IHCS in steroid naive
asthmatics (in non-smokers).
4. As a marker to follow longitudinally, particularly in poorly controlled asthmatics
contributing to assessing disease control, and response to changes in treatment (in
non-smokers).
5. It may become a method to assess the need for an exercise test in patients presenting
with a complaint of possible exercise induced bronchospasm - if No levels are normal
then an exercise test may not be required and investigations should proceed down
another avenue (in non-smokers).
The final, and brief, chapter will review where the research that I undertook contributed to
both the clarity and confusion of early knowledge in this area. I will review what I learnt from
the process of doing this research, writing up this thesis, and how this information has
ultimately altered my research and clinical practice'
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