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Table 7.5: Exhaled NO results with high and low background NO concentrations
Sublects Amblent NO Pre (hlgh NO) mean
(range)
One
(SD)
Two
(cAB)
Three
(cMB)
200.1 ppb 1 19.6ppb
(105.8-135.7ppb)
136.1ppb 94.9ppb
(84.0-100.8ppb)
91.4ppb 30.8ppb
(26.9-35.2ppb)
Reservolr (low NO)
mean (range)
202.4ppb
(154.1-225.4ppb)
134.0ppb
(102.9-163.8ppb)
32.9ppb
(20.3-38.6ppb)
Post (hlgh NO)
mean (range)
162.4ppb
(98.9-2a6.1ppb)
100.0ppb
(52.5-1s1.2ppb)
15.8ppb
(16.2-22.3ppb)
NB: The 'high' and 'bW NO note in the column headings refers to the ambient NO concentration
during each set of exhalations measured, with each result the mean of five exhalations. NO is
measured in parts per billion.
Table 7.6: Exhaled COz results with high and low background NO concentrations
Sublects Pre (hlsh NO)
mean (range)
One
(SD)
Two
(cAB)
Three
CMB
NB: The 'high' and 'low' NO note in the column headings refers to the ambient NO concentration
during each set of exhalations measured, with each result the mean of five exhalations. COz is
measured as percentage of totalgases and exhalation duration measured in seconds.
7.6 Methodological experiment five -
7.6.1 Hypothesis
effect of water consumption
l. Exhaled NO measurements will be affected by the consumption of water.
7.6.2 Aim
1. To compare NO levels measured by standard procedure before and after a set of testing in
which water was consumed immediately before each exhalation.
7.6.3 Procedure
Ten adult volunteers were enrolled (eight females) and all measurements were made by the t-
piece sampling system.
co25.2% (5.0-5.5)
Duration 52.2 secs
(45-60 seconds)
COzS.7To (5.6'5.8)
Duration 66.0 secs
(63-72 seconds)
COzS.5"/o (5.3'5.9)
Duration 55.2 secs
(48-63 seconds)
The first set of exhalations was carried out in the standard manner:
o The subject abstains from food and drink for 4 hours prior to the experiment.
168
Reservolr (low NO)
mean (range)
co2 5.1% (4.9'5.2)
Duration 54.0 secs
(36-63 seconds)
COz5.7o/" (5.6'5.8)
Duration 65.4 secs
(57-69 secs)
coz 5.6% (5.4-5.7)
Duration 58.2 secs
(54-69 seconds)
Post (hlgh NO)
mean (range)
co25.1"h (5.0-5.2)
Duration 51.6 secs
(39-63 seconds)
coz5.8To (5.7-5.9)
Duration 56.4 secs
(42-63 seconds)
COz5.5o/o (5.4-5.6)
Duration 57.0 secs
(54-60 seconds)