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Table 6.2 shows all the results on one subject to demonstrate that each of the testing
parameters are measured five times with the first set of conditions repeated. The parameters of
pressure and flow, although standardised voluntarily, were also measured to ensure they were
adequately controlled.
Table 6.2: Compete results for an individualsubject
NO In
pPb
COzas
% total
9a8e3
I have also included Table 6.3 with the mean results and ranges from all the subjects for
exhaled NO and COz, each the mean of 5 readings per subject. The coefficient of variation for
individuals was LTVo for the direct method and llVo for the t-piece method. The background
level of NO ranged from 1 to llppb; this did not alter the conclusions so was not taken into
account in the calculations.
Mouth
pressure
In mmHg
Tlme in
secondg
Time
NO
peak
Time
COz
peak
COz at
NO peak
NO at
COz
peak
Area
under the
culve
Direct 1 41 6.2 4.O 58.3 32.4 50.4 5.4 37.7 6.43
Direct 2 45 5.9 4.O 59.4 32.4 54.0 5.3 42.2 7.71
Direct 3 50 6.3 4.2 64.8 27.6 60.3 4.9 46.6 8.93
Direct 4 48 6.4 4.2 64.8 34.8 56.6 5.7 44.4 8.77
Direct 5 52 6.4 4.0 66.0 24.0 60.5 5.7 46.6 9.8
T-piece 1 10 6.8 4.0 60.6 6.0 48.0 3.7 8.9 1.27
T-piece 2 10 6.4 4.2 51.6 8.4 63.6 4.5 11.1 1.6
T-piece 3 10 6.6 4.1 58.3 12.O 63.5 4.9 13.1 1.2
T-piece 4 11 6.5 4.2 60.0 '12.0 58.8 4.9 8.8 1.5
T-piece 5 11 6.7 4.0 60.6 21.6 49.1 5.9 11.6 1.7
Table 6.3 NO and COz results from single exhalations in twelve adult subjects
Sublect
No.
Gender Peak
NO'
Range
NO
Dlrect
Peak
COzb
Range
COz
Ratlo
NO/COz
Peak
NO
Range
NO
t-plece
P€ak
COz
Range
COz
Ratlo
NO/COz
1 m 29.4 25-33 5.6 5.2-6.1 5.3 12.2 12-13 6.7 6.3-6.9 1.8
2 m 43.6 41-45 5.8 5.7-5.9 7.5 35.2 34-38 6.2 6.0-6.3 5.7
3 m 45.1 42-59 4.4 4.0-4.6 10.3 26.9 18-39 5.3 5.0-5.4 5.1
4 m 63.6 59-68 6.5 6.3-6.8 9.8 14.2 14-15 7.1 6.9-7.2 2.0
5 m 118.6 103-151 6.0 5.8-6.1 19.8 66.2 24-71 6.5 6.4-6.6 10.2
6 m 129.9 125-141 6.8 6.6-6.9 19.1 30.8 29-3'f! 7.2 7.1-7.3 4.3
7 I 47.2 41-52 6.3 5.9-6.4 7.5 10.4 10-1 1 6.7 6.5-6.8 1.6
I t 50.8 26-'110 5.2 5.2-5.5 9.4 30.3 29-32 5.4 5.3-5.6 5.6
I t 52.6 32-72 5.1 4.1-5.6 10.3 40.8 34-56 4.9 4.4-5.2 8.5
10 I 111 7l-160 5.6 5.4-5.6 19.8 92.7 83-102 5.3 5.2-5.3 1.7
11 t 123.9 26-147 6.8 6.7-6.9 18.5 72.7 69-74 6.7 6.5-6.9 10.7
12 I 166.8 143-189 5.5 5.2-5.8 30.3 50.8 46-56 6.2 6.0-6.3 8.2
t43