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Figure 7.6: Photographs <strong>of</strong> the changing ambient NO concentration recordings<br />

<strong>The</strong> ambient air NO concentration ranged from 91-200ppb during these experiments with a<br />

mean background NO concentration <strong>of</strong> 134.5ppb (SEM 11.9). <strong>The</strong> background concentration<br />

<strong>of</strong> the reservoir system was lppb (range 0-2ppb, SEM 0.2). Three subjects completed the<br />

experiment (mean age 37 years, all female). <strong>The</strong> mean plateau NO concentrations during the<br />

first set <strong>of</strong> exhalations with the high background NO was 94.9ppb (SEM 3.4ppb, range 84-<br />

l0lppb). <strong>The</strong> mean plateau exhaled NO concentration in the set <strong>of</strong> exhalations during which<br />

both the machine and subject were sampling from the NO-free reservoir system was 123.lppb<br />

(range 103-l64ppb, SEM I9.4). <strong>The</strong> mean plateau NO concentrations during the last set <strong>of</strong><br />

exhalations with the high background NO was 99.9ppb (SEM 20.5ppb, range 53-15lppb).<br />

Figure 7.7 shows a typical trace for one subject showing the rise to NO plateau during an<br />

exhalation made from the reservoir system and the fall to an NO plateau during an exhalation<br />

made from the high ambient NO. In the direct method, the NO level measured from the<br />

reservoir system was 41ppb (95Vo CI I9.9,62.7) greater than the measurements made before<br />

and after the reservoir system was used (see Figure 7.8). <strong>The</strong>re were no significant differences<br />

r66

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