NETTER - Neuroscience Flash Cards

Neurulation
1. Neural plate of forebrain
2. Neural groove
3. Neural folds
4. Future neural crest
5. Neural plate
6. Fused neural folds
7. Caudal neuropore
8. Neural crest
Comment: The neural plate invaginates and forms the neural
tube as the two margins of the neural folds fuse. This process of
neurulation starts centrally and moves both caudally and rostrally.
If the neural folds fail to fuse properly, dysraphic effects are seen
that involve altered development of associated muscles, bone,
skin, and meninges. The failure of the caudal neuropore to close
results in spina bifida, with failure of vertebral arches to fuse and
possible protrusion of meninges and neural tissues, exposing them
to the external environment. If the rostral neuropore fails to form,
anencephaly results, a failure of brain development with exposure of
the neural rudiments to the external environment, a lethal condition.
Overview of the Nervous System See book 8.2