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NETTER - Neuroscience Flash Cards

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Axial Sections through the Forebrain:

Head of the Caudate Nucleus

and Midthalamus

1. Genu of the corpus

callosum

2. Head of the caudate

nucleus

3. Anterior horn of the lateral

ventricle

4. Globus pallidus

5. Putamen

6. Optic radiations

7. Anterior limb of the internal

capsule

8. Genu of the internal

capsule

9. Posterior limb of the

internal capsule

10. Thalamus

11. Splenium of the corpus

callosum

Comment: The internal capsule reciprocally interconnects cortex

and more caudal structures. The anterior limb carries cortical

projections to the striatum and pontine nuclei (corticopontocerebellar

system) and has reciprocal connections with important thalamic

structures such as the medial dorsal and anterior nuclei. The genu

carries corticobulbar axons destined for brain stem nuclei regulation,

particularly motor cranial nerve nuclei. The posterior limb conveys

major descending corticospinal, corticorubral, and corticoreticular

fibers; major ascending sensory connections for the somatosensory

and trigeminal system; and, posteriorly, visual and auditory

radiations. The internal capsule is susceptible to middle cerebral

artery lesions, particularly narrow lenticulostriate arteries. A vascular

lesion of the posterior limb of the internal capsule results (long term,

after resolution of the flaccid stage of shock) in contralateral spastic

hemiplegia with hypertonus, hyperreflexia, flexed posture of the

upper limb and extended and internally rotated posture of the lower

limb, and pathological reflexes (e.g., plantar extensor response,

possibly clonus). Such a lesion also produces loss of sensation on

the contralateral body. If the genu of the internal capsule is involved

in the lesion, a contralateral drooping lower face (central facial palsy)

is seem due to removal of control of the corticobulbar system from

regulation of the contralateral facial nerve motor nucleus for muscles

of facial expression for the lower face.

Regional Neuroscience See book 13.6B

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