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NETTER - Neuroscience Flash Cards

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Central Control of Eye Movements

1. Frontal eye fields (Area 8)

2. Occipital eye fields (Areas 17, 18, 19)

3. Interstitial nucleus of Cajal

4. Superior colliculus

5. Oculomotor nucleus

6. Abducens internuclear neuronal projection

7. Trochlear nucleus

8. Medial longitudinal fasciculi

9. Abducens nucleus

10. Parapontine reticular formation (PPRF)

11. Vestibular ganglion and nerve

12. Vestibular nuclei

13. Corticoreticular fibers

Comment: Central control of eye movements is achieved through

the coordination of extraocular motor nuclei for CNs III, IV, and VI;

this is achieved through the parapontine reticular formation (PPRF,

horizontal gaze center). The PPRF receives input from the vestibular

nuclei, the deep layers of the superior colliculus (reflecting inputs

from V1, V2, and V3), the frontal eye fields of the cerebral cortex, and

the interstitial nucleus of Cajal (reflecting inputs from the vestibular

nuclei and the frontal eye fields). The PPRF drives the ipsilateral

abducens nucleus for movement of the lateral rectus muscle,

and the contralateral oculomotor nucleus (via interneurons in the

abducens nucleus) for movement of the medial rectus muscle of the

contralateral side, thereby coordinating horizontal eye movements.

The interstitial nucleus of Cajal helps to coordinate vertical and

oblique eye movements. Secondary sensory vestibular projections

also terminate in the extraocular motor CNN. Axons interconnecting

the extraocular motor nuclei travel through the medial longitudinal

fasciculus.

Systemic Neuroscience See book 15.14

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