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NETTER - Neuroscience Flash Cards

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Development of the Pituitary Gland

1. Infundibular process

2. Brain

3. Rathke’s pouch

4. Infundibulum

5. Pars distalis

6. Pars tuberalis

7. Pars nervosa

8. Pars intermedia

Comment: The posterior lobe of the pituitary (neurohypophysis,

pars nervosa) derives from the brain and contains axonal processes

from the hypothalamus that secrete oxytocin and vasopressin into

the general circulation. The anterior lobe (adenohypophysis) derives

from the roof of the stomodeum and encircles the base of the

neurohypophysis. The adenohypophysis contains pituicytes that

respond to releasing and inhibitory factors produced by neurons,

secreted into the hypophyseal-portal vascular system (a private

vascular channel) at the contact zone of the median eminence.

Pituicytes can be the source of tumor development (e.g., growth

hormone–secreting cells), producing endocrine deficits and mass

effects from impingment on the nearby optic chiasm.

Overview of the Nervous System See book 8.22

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