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NETTER - Neuroscience Flash Cards

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Coronal Sections through the Forebrain:

Head of the Caudate Nucleus and

Nucleus Accumbens

1. Cingulate gyrus

2. Body of the corpus callosum

3. Septum pellucidum

4. Claustrum

5. Insular cortex

6. Lateral fissure

7. Temporal lobe

8. Amygdala

9. Frontal pole of the lateral ventricle

10. Head of the caudate nucleus

11. Anterior limb of the internal capsule

12. Putamen

13. Nucleus accumbens

14. Optic chiasm

Comment: The nucleus accumbens is found at the anterior end

of the striatum in the ventral part of the forebrain anterior to the

anterior limb of the internal capsule. It receives extensive inputs from

limbic structures such as the amygdala, the hippocampal formation,

and the bed nucleus of the stria terminalis. Major dopaminergic

inputs from the ventral tegmental area of the midbrain travel via

the mesolimbic dopaminergic pathway to supply the nucleus

accumbens with a dense bed of terminals. The nucleus accumbens

is a key structure for motivational states and addictive behaviors,

driven by dopaminergic neurotransmission. The nucleus accumbens

also is a principal region for brain circuitry associated with reward,

such as joy, pleasure, and gratification. This nucleus has looped

circuitry through the thalamus and cortex that contributes to motor

expression of emotional responses and their accompanying gestures

and behaviors.

Regional Neuroscience See book 13.12B

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