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Neuroimmunomodulation1142313121148910567Systemic Neuroscience 3-52
Neuroimmunomodulation1. Limbic forebrain areas2. Paraventricular nucleus of thehypothalamus3. Median eminence4. Brain stem nuclei5. Nucleus of the solitary tract6. Preganglionic sympatheticaxons7. Postganglionic sympatheticnoradrenergic axons8. Epinephrine andnorepinephrine9. Cortisol10. ACTH11. Site of action of releasing andinhibitory factors12. Release of anterior pituitaryhormones13. Cytokine and inflammatorymediator feedback to the brainand pituitary14. Cerebral cortexComment: Neurohormones from the anterior pituitary and sympatheticneuronal activity can influence a wide range of immune responses. Influencesfrom the cerebral cortex, limbic forebrain structures, and brain stem providethe neuronal circuitry and substrate for behavioral influence, emotionalresponsiveness, chronic stressors, and positive complementary and behavioralinfluences that modulate immune responses through these neurohormonesand the autonomic nervous system. Sympathetic postganglionic noradrenergicneurons directly contact immunocytes and vasculature in virtually all immuneorgans, including the parenchyma of bone marrow, thymus, spleen, lymphnodes, and mucosal- and skin-associated immune tissue. Virtually all anteriorpituitary hormones, target organ hormones, and even some releasing-factorhormones (CRF) exert immunomodulatory influences. Cortisol from thehypothalamo-pituitary-adrenal (HPA) axis and norepinephrine and epinephrinefrom the sympathoadrenal system are particularly important in modulatingimmune reactivity as a component of the stress response, influencing primaryimmune cell proliferation and migration; antigen recognition, presentation, andprocessing; lymphocyte trafficking; generation of cell-mediated and humoralimmune responses, including Th1 and Th2 activation; innate immune reactivity(natural killer cell activity, macrophage functions, others); immunoglobulinselection and production; and many other functions. Cytokines can modulateneural-immune interactions through induction of neurotransmitter secretion andmodulation of immunocyte receptivity to neural signaling.Systemic Neuroscience See book 16.24
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Netter’sNeuroscienceFlash CardsSe
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PrefaceNetter’s Neuroscience Flas
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Table of ContentsSection 1 : Overvi
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1 Overview of the Nervous SystemPla
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Overview of the Nervous SystemPlate
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Neuronal Structure12345 67891011Ove
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Neuronal Cell Types12111210Red:Moto
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Glial Cell Types10918265374Overview
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Blood-Brain Barrier162543Overview o
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Myelination of CNS and PNS AxonsCen
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Synaptic MorphologyA. Schematic of
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Overview of the Nervous System 1-7C
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Foramina in the Base ofthe Adult Sk
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Bony Framework of the Headand Neck7
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Schematic of the Meninges and Their
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Hematomas4321765Overview of the Ner
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Surface Anatomy of the Forebrain:La
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Lateral View of the Forebrain:Funct
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Anatomy of the Medial (Midsagittal)
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Anatomy of the Basal Surface ofthe
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A. Coronal viewBrain Imaging: Compu
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Brain Imaging: Magnetic ResonanceIm
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Brain Imaging: Magnetic ResonanceIm
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Horizontal Brain Sections Showingth
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Major Limbic Forebrain Structures76
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Color Imaging of the Corpus Callosu
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Hippocampal Formation and FornixA.
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Thalamic Anatomy11321211104356789Ov
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Thalamic Nuclei12354876910111514121
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Brain Stem Surface Anatomy:Posterol
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Brain Stem Surface Anatomy:Anterior
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Cerebellar Anatomy: Internal Featur
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Spinal Column: Bony Anatomy12345678
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Spinal Cord: Gross Anatomy In Situ1
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Spinal Cord: Its Meninges andSpinal
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Spinal Cord: Cross-SectionalAnatomy
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Spinal Cord: White and Gray Matter1
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Ventricular Anatomy1112345671098Ove
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Ventricular Anatomy in CoronalForeb
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Anatomy of the Fourth Ventricle:Lat
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A. Axial viewMagnetic Resonance Ima
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Circulation of the Cerebrospinal Fl
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Arterial Supply to the Brainand Men
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Arterial Distribution to the Brain:
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Circle of Willis: Schematic Illustr
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Magnetic Resonance Angiography:Coro
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Vertebrobasilar Arterial System1234
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Arterial Blood Supply to the Spinal
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Arterial Supply to the Spinal Cord:
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Meninges and SuperficialCerebral Ve
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Venous Sinuses123458109675118241096
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Deep Venous Drainage of the Brain:R
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Magnetic Resonance Venography123451
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Neurulation1Level of section4523432
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Neural Tube Development andNeural C
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Development of Peripheral Axons2134
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Early Brain Development:36-Day-Old
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Early Brain Development: 49-Day-Old
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Development of the Eye and Orbit1 2
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Development of the Ear326574112aLat
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Development of the Pituitary Gland1
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Development of the Ventricles134312
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2Regional NeurosciencePlates 2-1 to
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Regional NeurosciencePlates 2-1 to
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2-82 Hypothalamus and Pituitary Gla
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Spinal Cord and PNS SchematicSensor
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Anatomy of a Peripheral Nerve1Compr
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Cutaneous Receptors1 2 3 4567Region
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Neuromuscular Junction6714512321110
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Dermatomal Distribution124 365789Re
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Cutaneous Nerves ofthe Head and Nec
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Cervical Plexus12345111067981211108
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Phrenic Nerve18756423Regional Neuro
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Thoracic Nerves123 4561079 8Regiona
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Brachial PlexusC56SuperiorC6C7435La
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Dermatomes of the Upper Limb7Anteri
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Cutaneous Innervation of the UpperL
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Scapular, Axillary, and RadialNerve
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Radial Nerve in the Forearm12345789
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Musculocutaneous Nerve1116987102354
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Median Nerve12 6734Cutaneousinnerva
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Ulnar Nerve12Cutaneousinnervation34
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Lumbar Plexus1345267891011213456813
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Sacral and Coccygeal Plexuses978106
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Femoral and Lateral FemoralCutaneou
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Obturator Nerve12345136789101112Reg
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Sciatic and Posterior FemoralCutane
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Tibial Nerve127Cutaneousinnervation
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Common Peroneal Nerve101Cutaneousin
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Schematic of the AutonomicNervous S
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Autonomic Distribution to the Heada
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Autonomic Distribution to the Heada
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Autonomic Distribution to the Eye14
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Schematic of Pterygopalatine andSub
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Thoracic Sympathetic Chain andSplan
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Innervation ofthe Tracheobronchial
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Innervation of the Heart2 139410115
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Abdominal Nerves and Ganglia1243567
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Nerves of the EsophagusAnterior vie
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Nerves of the Stomach and Duodenum1
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Nerves of the Small Intestine123456
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Nerves of the Large Intestine123154
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Enteric Nervous SystemVagus nervesT
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Autonomic Innervation of the Livera
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Autonomic Innervationof the Pancrea
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Innervation of the Adrenal Gland1T1
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Autonomic Pelvic Nervesand Ganglia1
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Nerves of the Kidneys, Ureters,and
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Innervation of the MaleReproductive
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Innervation of the FemaleReproducti
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Cytoarchitecture of the SpinalCord
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C7 Spinal Cord Cross SectionDescend
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T8 Spinal Cord Cross SectionDescend
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L3 Spinal Cord Cross SectionDescend
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S3 Spinal Cord Cross SectionDescend
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Spinal Cord Imaging123456789Regiona
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Spinal Somatic Reflex Pathways1234F
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Muscle and Joint Receptorsand Muscl
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Brain Stem Cross Section:Medulla-Sp
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Brain Stem Cross Section: Medullaat
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Brain Stem Cross Section:Medullo-Po
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Brain Stem Cross Section: Pons atth
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Brain Stem Cross Section: Pons atth
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Brain Stem Cross Sections: Pons att
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Brain Stem Cross Section:Pons-Midbr
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Brain Stem Cross Section: Midbrain
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Brain Stem Cross Section: Midbrain
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Brain Stem Cross Section:Midbrain-D
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Cranial Nerves: Basal View of the B
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Cranial Nerves and Their Nuclei:Sch
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Nerves of the Orbit1312123451110967
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Extraocular Cranial Nerves123456789
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Trigeminal Nerve (CN V)4 3 2 156789
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Facial Nerve (CN VII)12345678910 11
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Vestibulocochlear Nerve (CN VIII)23
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Glossopharyngeal Nerve (CN IX)Senso
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Vagus Nerve (CN X)12345761110981213
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Accessory Nerve (CN XI)125673489101
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Hypoglossal Nerve (CN XII)123456Mot
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Reticular Formation and NucleiA. Th
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Sleep-Wakefulness ControlThalamus10
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Cerebellar Organization:Lobes and R
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Cerebellar Anatomy: Deep Nucleiand
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Thalamic Anatomy andInterconnection
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Hypothalamus and Pituitary Gland123
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Hypothalamic Nuclei1Lateralventricl
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Axial Sections throughthe Forebrain
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Axial Sections throughthe Forebrain
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Axial Sections through the Forebrai
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Axial Section through the Forebrain
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Coronal Sections throughthe Forebra
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Coronal Sections through the Forebr
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Cortical Association Pathways4Ms IM
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Major Cortical Association Bundles1
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Color Imaging of Projection Pathway
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Noradrenergic Pathways612345Regiona
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Serotonergic Pathways2 1345678910Re
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Dopaminergic Pathways1234567Regiona
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Central Cholinergic Pathways123456R
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Olfactory Nerves213546789105346Regi
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3Systemic NeurosciencePlates 3-1 to
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Systemic NeurosciencePlates 3-1 to
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Somatosensory Afferents tothe Spina
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Somatosensory System:Spinocerebella
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Somatosensory System: Dorsal Column
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Somatosensory System: Spinothalamic
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Mechanisms of Neuropathic Pain andS
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Descending Control of Pain Processi
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Trigeminal Sensory and AssociatedSe
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Taste PathwaysCerebrum1234Pons657Me
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Peripheral Pathways forSound Recept
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Bony and Membranous Labyrinths11723
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VIII Nerve Innervation of Hair Cell
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Auditory Pathways2134756Low tonesMi
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Centrifugal (Efferent)Auditory Path
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Vestibular ReceptorsA. Membranous l
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Vestibular Pathways12123456111097Lo
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NystagmusSlow phaseRapid phase(sacc
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Anatomy of the Eye12345678910111817
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Anterior and Posterior Chambersof t
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Retina: Retinal LayersRetinallayers
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Arteries and Veins of the Eye123456
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Optic ChiasmSuperiorTemporalNasal12
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Visual Pathways: Retinal Projection
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Visual Pathway: Retino-Geniculo-Cal
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Visual Pathways in the Parietaland
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Distribution of Lower Motor Neurons
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Cortical Efferent PathwaysCerebral
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Page 412 and 413: Rubrospinal Tract12341089576Systemi
Page 414 and 415: Vestibulospinal Tracts12 Vestibular
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Page 418 and 419: Central Control of Eye Movements123
Page 420 and 421: Central Control of Respiration12341
Page 422 and 423: Cerebellar Neuronal CircuitryExcita
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Page 428 and 429: Connections of the Basal GangliaCon
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Page 432 and 433: Sections through hypothalamus ISect
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Page 446 and 447: Circumventricular Organs126543Syste
Page 448 and 449: Hypophysial Portal VasculatureBlood
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Page 452 and 453: Posterior Pituitary (Neurohypophysi
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Page 458 and 459: Anatomy of the Limbic ForebrainMajo
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Page 468 and 469: Major Connectionsof the Cingulate C
Page 470 and 471: Olfactory Pathways12345613141516171
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NETTER - Neuroscience Flash Cards

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