Références bibliographiques Baker, R.L., Mwamachi, D.M., Audho, J.O., Aduda, E.O., Thorpe, W., 1998, Resistance of Galla and Small East African goats in the sub-humid tropics to <strong>gastro</strong>intestinal nemato<strong>de</strong> infections and the peri-parturient rise in faecal egg counts. Vet Parasitol 79, 53-64. Balic, A., Bowles, V.M., Meeusen, E.N., 2000, The immunobiology of <strong>gastro</strong>intestinal nemato<strong>de</strong> infections in ruminants. Adv Parasitol 45, 181-241. Balic, A., Harcus, Y., Holland, M.J., Maizels, R.M., 2004, Selective maturation of <strong>de</strong>ndritic cells by Nippostrongylus brasiliensis-secreted proteins drives Th2 immune responses. Eur J Immunol 34, 3047- 3059. Bancroft, A.J., Else, K.J., Grencis, R.K., 1994, Low-level infection with Trichuris muris significantly affects the polarization of the CD4 response. Eur J Immunol 24, 3113-3118. Bancroft, A.J., McKenzie, A.N., Grencis, R.K., 1998, A critical role for IL-13 in resistance to intestinal nemato<strong>de</strong> infection. J Immunol 160, 3453-3461. Bancroft, A.J., Else, K.J., Humphreys, N.E., Grencis, R.K., 2001, The effect of challenge and trickle Trichuris muris infections on the polarisation of the immune response. Int J Parasitol 31, 1627-1637. Barger, I.A., 1985a, The statistical distribution of trichostrongylid nemato<strong><strong>de</strong>s</strong> in grazing lambs. Int J Parasitol 15, 645-649. Barger, I.A., Le Jambre, L.F., Georgi, J.R., Davies, H.I., 1985b, Regulation of Haemonchus contortus <strong>populations</strong> in sheep exposed to continuous infection. Int J Parasitol 15, 529-533. Barger, I.A., Le Jambre, L.F., 1988, Regulation of Haemonchus contortus <strong>populations</strong> in sheep: mortality of established worms. Int J Parasitol 18, 269-273. Barger, I.A., 1989, Genetic resistance of hosts and its influence on epi<strong>de</strong>miology. Vet Parasitol 32, 21-35. Barker, I.K., 1973, A study of the pathogenesis of Trichostrongylus colubriformis infection in lambs with observations on the contribution of <strong>gastro</strong>intestinal plasma loss. Int J Parasitol 3, 743-757. Barnes, E.H., Dobson, R.J., 1990, Population dynamics of Trichostrongylus colubriformis in sheep: mathematical mo<strong>de</strong>l of worm fecundity. Int J Parasitol 20, 375-380. Barnes, E.H., Dobson, R.J., 1993, Persistence of acquired immunity to Trichostrongylus colubriformis in sheep after termination of infection. Int J Parasitol 23, 1019-1026. Basset, C., Holton, J., O'Mahony, R., Roitt, I., 2003, Innate immunity and pathogen-host interaction. Vaccine 21 Suppl 2, S12-23. Beh, K.J., 1987, Production and characterization of monoclonal antibodies specific for sheep IgG subclasses IgG1 or IgG2. Vet Immunol Immunopathol 14, 187-196. Beh, K.J., 1988, Monoclonal antibodies against sheep immunoglobulin light chain, IgM and IgA. Vet Immunol Immunopathol 18, 19-27. Beh, K.J., Callaghan, M.J., Hulme, D.J., Leish, Z., DiIenno, K., Lenane, I., 1998, A search for genes affecting <strong>gastro</strong>intestinal parasite resistance in sheep. Proceedings of the 26th International Conference on Animal Genetics, Abstract E033, 102-103. Beh, K.J., Hulme, D.J., Callaghan, M.J., Leish, Z., Lenane, I., Windon, R.G., Maddox, J.F., 2002, A genome scan for quantitative trait loci affecting resistance to Trichostrongylus colubriformis in sheep. Anim Genet 33, 97-106. Behm, C.A., Ovington, K.S., 2000, The role of eosinophils in parasitic helminth infections: insights from genetically modified mice. Parasitol Today 16, 202-209. 212
Références bibliographiques Behnke, J.M., Barnard, C.J., Wakelin, D., 1992, Un<strong>de</strong>rstanding chronic nemato<strong>de</strong> infections: evolutionary consi<strong>de</strong>rations, current hypotheses and the way forward. Int J Parasitol 22, 861-907. Behnke, J.M., Iraqi, F., Menge, D., Baker, R.L., Gibson, J., Wakelin, D., 2003, Chasing the genes that control resistance to <strong>gastro</strong>intestinal nemato<strong><strong>de</strong>s</strong>. J Helminthol 77, 99-110. Bell, A., Ranford-Cartwright, L., 2002, Real-time quantitative PCR in parasitology. Trends Parasitol 18, 338. Benavi<strong><strong>de</strong>s</strong>, M.V., Weimer, T.A., Borba, M.F.S., Berne, M.E.A., Sacco, A.M.S., 2002, Associations between microsatellite markers of sheep chromosome 5 and faecal egg counts. Small Ruminant Research 46, 97- 105. Bendixsen, T., Bosward, K.L., Emery, D.L., 2003, Production and characterisation of monoclonal antibodies to ovine interleukin-5. Parasitol Int 52, 281-290. Béné, M.C., Faure, G.C., 2000, Immunité innée et congnitive aux interfaces muqueuses. Revue française <strong><strong>de</strong>s</strong> laboratoires 327, 49-55. Beugnet, F., Gevrey, J., Kerboeuf, D., 1997, Les en<strong>de</strong>ctoci<strong><strong>de</strong>s</strong> : mo<strong>de</strong> d'action et d'utilisation. Point vétérinaire Numéro Spécial "Parasitologie <strong><strong>de</strong>s</strong> Ruminants" 28, 133-137. Beugnet, F., Kerboeuf, D., 1997, La résistance aux antiparasitaires chez les parasites <strong><strong>de</strong>s</strong> ruminants. Point vétérinaire Numéro Spécial "Parasitologie <strong><strong>de</strong>s</strong> Ruminants" 28, 167-174. Bishop, S.C., Stear, M.J., 2000, The use of a gamma-type function to assess the relationship between the number of adult Teladorsagia circumcincta and total egg output. Parasitology 121 ( Pt 4), 435-440. Bisset, S.A., Morris, C.A., Squire, D.R., Hickey, S.M., Wheeler, M., 1994, Genetics of resilience to nemato<strong>de</strong> parasites in sheep. N Zeal J Agric Research 37, 521-534. Bisset, S.A., Vlassoff, A., Douch, P.G., Jonas, W.E., West, C.J., Green, R.S., 1996, Nemato<strong>de</strong> bur<strong>de</strong>ns and immunological responses following natural challenge in Romney lambs selectively bred for low or high faecal worm egg count. Vet Parasitol 61, 249-263. Bisset, S.A., Vlassoff, A., West, C.J., 1991, Proceedings 21st seminar of the sheep and beef society. New Zeland Veterinary Society, 83. Bjorn, H., 1994, Workshop summary: anthelmintic resistance. Vet Parasitol 54, 321-325. Blackburn, C.C., Selkirk, M.E., 1992, Inactivation of platelet-activating factor by a putative acetylhydrolase from the <strong>gastro</strong>intestinal nemato<strong>de</strong> parasite Nippostrongylus brasiliensis. Immunology 75, 41-46. Blackhall, W.J., Prichard, R.K., Beech, R.N., 2003, Selection at a gamma-aminobutyric acid receptor gene in Haemonchus contortus resistant to avermectins/milbemycins. Mol Biochem Parasitol 131, 137-145. Blitz, N.M., Gibbs, H.C., 1971, An observation on the maturation of arrested Haemonchus contortus larvae in sheep. Can J Comp Med 35, 178-179. Borgstee<strong>de</strong>, F.H., Roos, M.H., Smith, G., Prichard, R.K., 1996, Workshop summary: anthelmintic resistance. Vet Parasitol 64, 129-132. Bottjer, K.P., Klesius, P.H., Bone, L.W., 1985, Effects of host serum on feeding by Trichostrongylus colubriformis (nematoda). Parasite Immunol 7, 1-9. Bowman, D.D., 1999, Georgi's Parasitology for Veterinarians, Seventh Edition Phila<strong>de</strong>lphia, 414 p. Bown, M.D., Poppi, D.P., Sykes, A.R., 1991, The effect of post-ruminal infusion of protein or energy on the physiopathology of Trichostrongylus colubriformis infection and body composition in lambs. Aust J Agric Res 42, 253-267. 213
- Page 1 and 2:
N° d’ordre : 2346 THESE présent
- Page 3 and 4:
A mon très cher et respecté « co
- Page 5 and 6:
4.3.3. Mise en place et rôle des e
- Page 7 and 8:
ANNEXE A L’ARTICLE « HAEMONCHUS
- Page 9 and 10:
Un problème économique … et sci
- Page 11 and 12:
1. GENERALITES SUR LES STRONGLES GA
- Page 13 and 14:
1.2. Le cycle biologique des Tricho
- Page 15 and 16:
Contexte bibliographique 1.3. Les d
- Page 17 and 18:
Contexte bibliographique • Haemon
- Page 19 and 20:
Contexte bibliographique Les princi
- Page 21 and 22:
Famille Molécule Noms déposés Be
- Page 23 and 24:
Contexte bibliographique été déc
- Page 25 and 26:
Contexte bibliographique Pendant de
- Page 27 and 28:
3.1. Tarir les sources de contamina
- Page 29 and 30:
Contexte bibliographique germer dan
- Page 31 and 32:
Contexte bibliographique Le tableau
- Page 33 and 34:
*La vaccination contre Trichostrong
- Page 35 and 36:
3.2.3. La sélection de la résista
- Page 37 and 38:
LIEU DE L’ETUDE RACES ETUDIEES /
- Page 39 and 40:
*Sélection au sein d’une même r
- Page 41 and 42:
Contexte bibliographique sont pas r
- Page 43 and 44:
Contexte bibliographique responders
- Page 45 and 46:
Contexte bibliographique et al., 20
- Page 47 and 48:
Contexte bibliographique Toutefois,
- Page 49 and 50:
Contexte bibliographique 4. LA REPO
- Page 51 and 52:
Contexte bibliographique Dans le do
- Page 53 and 54:
Contexte bibliographique et Janeway
- Page 55 and 56:
Contexte bibliographique réponses
- Page 57 and 58:
Contexte bibliographique americanus
- Page 59 and 60:
Contexte bibliographique - une mast
- Page 61 and 62:
Contexte bibliographique Le mécani
- Page 63 and 64:
Contexte bibliographique cellulaire
- Page 65 and 66:
Contexte bibliographique suppressio
- Page 67 and 68:
Contexte bibliographique de résist
- Page 69 and 70:
Contexte bibliographique Ainsi, l
- Page 71 and 72:
*Réduction de la taille des vers a
- Page 73 and 74:
4.3.5. Régulation de la réponse i
- Page 75 and 76:
Contexte bibliographique d’infest
- Page 77 and 78:
Contexte bibliographique Figure n°
- Page 79 and 80:
Objectifs des travaux de thèse CHA
- Page 81 and 82:
Objectifs des travaux de thèse Dan
- Page 83 and 84:
1. MODELES EXPERIMENTAUX 1.1. Les a
- Page 85 and 86:
Procédures expérimentales mais n
- Page 87 and 88:
Procédures expérimentales 2.3. Et
- Page 89 and 90:
Procédures expérimentales être e
- Page 91 and 92:
Procédures expérimentales suivie
- Page 93 and 94:
Procédures expérimentales avec un
- Page 95 and 96:
Procédures expérimentales de la p
- Page 97 and 98:
ISOTYPE Type d’antigène Concentr
- Page 99 and 100:
Procédures expérimentales (i) des
- Page 101 and 102:
6.1.4. Immunohistochimie sur coupes
- Page 103 and 104:
Procédures expérimentales éviden
- Page 105 and 106:
Procédures expérimentales - cultu
- Page 107 and 108:
Résultats CHAPITRE V : RESULTATS 1
- Page 109 and 110:
Résultats - à la polarisation Th1
- Page 111 and 112:
Vet. Res. 37 (2006) 1-16 © INRA, E
- Page 113 and 114:
ut no clinical signs of coccidiosis
- Page 115 and 116:
gene sequence was not known (Eotaxi
- Page 117 and 118:
-20 °C acetone bath before drying.
- Page 119 and 120:
Th 2 response in H. contortus infec
- Page 121 and 122:
significant systemic CEL 3 specific
- Page 123 and 124:
3.5.4. Reduced fecal egg output At
- Page 125 and 126:
populations in sheep exposed to con
- Page 127 and 128:
Résultats Annexe à l’article «
- Page 129 and 130:
Résultats Les corrélations entre
- Page 131 and 132:
Article II : Immune responses in la
- Page 133 and 134:
1. INTRODUCTION Résultats Due to t
- Page 135 and 136:
2. MATERIAL AND METHODS 2.1. Experi
- Page 137 and 138:
Résultats RNA were digested with 1
- Page 139 and 140:
Résultats for 2h at room temperatu
- Page 141 and 142:
Résultats clone Ki-M6, Serotec, 1:
- Page 143 and 144:
3. RESULTS 3.1. Dynamics of the wor
- Page 145 and 146:
3.4. Dynamics of the duodenal cellu
- Page 147 and 148:
4. DISCUSSION Résultats In this st
- Page 149 and 150:
Résultats nematode infections elic
- Page 151 and 152:
REFERENCES Résultats Balic, A., Bo
- Page 153 and 154:
Résultats Pernthaner, A., Vlassoff
- Page 155 and 156:
Table 1 : Schematic description of
- Page 157 and 158:
Table 3 : Reagents and procedures u
- Page 159 and 160:
Table 5 : Correlations between cell
- Page 165 and 166: Résultats PARTIE II : ETUDE COMPAR
- Page 167 and 168: Résultats Article III : Dynamics o
- Page 169 and 170: 1 - INTRODUCTION Résultats The con
- Page 171 and 172: 2 - MATERIALS AND METHODS 2.1. Expe
- Page 173 and 174: Résultats of water. Larvae were co
- Page 175 and 176: Résultats protocol. The purity of
- Page 177 and 178: Résultats macrophages/monocytes (m
- Page 179 and 180: Résultats (L4 to adults) were pres
- Page 181 and 182: Résultats in INRA 401 lambs and bl
- Page 183 and 184: Résultats experimental protocols,
- Page 185 and 186: Résultats terms of female size, eg
- Page 187 and 188: Résultats Gauly, M., Kraus, M., Ve
- Page 189 and 190: Table 1 : Schematic description of
- Page 191 and 192: Table 3 : Total worm burden, length
- Page 193 and 194: Epg Epg 30000 25000 20000 15000 100
- Page 195 and 196: Résultats 195
- Page 197 and 198: Discussion générale CHAPITRE VI :
- Page 199 and 200: Discussion générale l’excrétio
- Page 201 and 202: Discussion générale effectrices,
- Page 203 and 204: Discussion générale chez des ovin
- Page 205 and 206: Discussion générale entre J4 et J
- Page 207 and 208: Discussion générale souris infest
- Page 209 and 210: Discussion générale connaissance
- Page 211: Références bibliographiques Adams
- Page 215 and 216: Références bibliographiques Claer
- Page 217 and 218: Références bibliographiques cytok
- Page 219 and 220: Références bibliographiques Gibbo
- Page 221 and 222: Références bibliographiques Jacks
- Page 223 and 224: Références bibliographiques Lee,
- Page 225 and 226: Références bibliographiques Monta
- Page 227 and 228: Références bibliographiques Pfeff
- Page 229 and 230: Références bibliographiques Sher,
- Page 231 and 232: Références bibliographiques paras
- Page 233 and 234: Références bibliographiques Yazwi