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Richtlijn: Niet-kleincellig longcarcinoom (2.0) - Kwaliteitskoepel

Richtlijn: Niet-kleincellig longcarcinoom (2.0) - Kwaliteitskoepel

Richtlijn: Niet-kleincellig longcarcinoom (2.0) - Kwaliteitskoepel

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<strong>Richtlijn</strong>: <strong>Niet</strong>-<strong>kleincellig</strong> <strong>longcarcinoom</strong> (<strong>2.0</strong>)stadium IIBT2T3N1N0M0M0stadium IIIAT1T2T3N2N2N1,N2M0M0M0stadium IIIBelke TT4N3elke NM0M0stadium IV elke T elke N M1Tabel 3: Hulpmiddel voor het omzetten van de 6 e naar de 7 e TNM classificatie209 208Descriptors, Proposed T and M Categories, and Proposed Stage GroupingsSixth edition T/M Proposed N0 N1 N2 N3DescriptorT/MT1 (< 2 cm) T1a IA IIA IIIA IIIBT1 (> 2-3 cm) T1b IA IIA IIIA IIIBT2 (> 3-< 5 cm) T2a IB IIA IIIA IIIBT2 (> 5-7 cm) T2b IIA IIB IIIA IIIBT2 (> 7 cm) T3 IIB IIIA IIIA IIIBT3 invasion IIB IIIA IIIA IIIBT4 (same lobeIIB IIIA IIIA IIIBnodules)T4 (extension) T4 IIIA IIIA IIIB IIIBM1 (ipsilateral lung) IIIA IIIA IIIB IIIBT4 (pleural effusion) M1a IV IV IV IVM1 (contralateral lung) IV IV IV IVM1 (distant) M1b IV IV IV IVCells in bold indicate a change from the sixth edition for a particular TNM categoryTabel 4: Veranderingen in vetgedrukt aangegeven tussen 6 e en 7 e editie van de TNM classificatie.TX Positive cytology onlyT1 < 3 cmT1a ≥ 2 cmT1b >2-3 cmT2 Main bronchus ≥ 2 cm from carina, invades visceral pleura,partial atelectasisT2a >3-5 cmT2b >5-7 cmT3 >7 cm, separate tumour nodule(s) in same lobeChest wall, diaphragm, pericardium, mediastinal pleura, mainbronchus >2cm from carina, total atelectasisT4 Separate tumour nodule(s) in a different ipsilateral lobeMediastinum, heart, great vessels, carina, trachea,oesophagus, vertebraN1 Ipsilateral peribronchial, ipsilateral hilarN2 Subcarinal, ipsilateral mediastinalN3 Contralateralmediastinal or hilar, scalene or supraclavicularM1 Distant metastasisM1a Separate tumour nodule(s) in a contralateral lobe; pleuralnodules or malignant pleural or pericardial effusionM1b Distant metastasisFiguur 1: Regionale klierstations, benaming ten behoeve van longkankerstadiering volgens de7 e editie IASLCConform het voorstel van de IASLC schuift de grens tussen niveau 2 en 4 links en rechts van de arbitraireanatomische middenlijn van de trachea (ATS systeem) naar de linker laterale wand van de tracheaaangezien deze beter overeenkomt met het lymfedrainage patroon.06/09/2011 <strong>Niet</strong>-<strong>kleincellig</strong> <strong>longcarcinoom</strong> (<strong>2.0</strong>) 90

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