Title: Alternative Sweeteners

Neohesperidin Dihydrochalcone 103
55. RM Horowitz, B Gentili. Dihydrochalcone xylosides and their use as sweetening
agents. US Patent No. 3,826,856 (July 30, 1974).
56. GP Rizzi. Dihydrochalcone sweetening agents. US Patent No. 3,739,064 (June 12,
1973).
57. F Caccia, R Dispenza, G Fonza, C Fuganti, L Malpezzi, A Mele. Structure of neohesperidin
dihydrochalcone/β-cyclodextrin inclusion complex: NMR, MS, and X-ray
spectroscopy investigation. J Agric Food Chem 46:1500–1505, 1998.
58. GW von Rymon Lipinsky, E Lück. Sweetener mixture. US Patent No. 4,158,068
(1979).
59. MR Jenner. Sweetening agents. Eur Patent Application No. 0 507 598 A1 (1992).
60. HJ Chung. Measurement of synergistic effects of binary sweetener mixtures. J Food
Sci Nutr 2:291–295, 1997.
61. MG Lindley, PK Beyts, I Canales, F Borrego. Flavor modifying characteristics of
the intense sweetener neohesperidin dihydrochalcone. J Food Sci 58:592–594666,
1993.
62. MG Lindley. Neohesperidin dihydrochalcone: Recent findings and technical advances.
In: TH Grenby, ed. Advances in Sweeteners. Glasgow, UK: Chapman &
Hall, 1996, pp 240–252.
63. R Foguet, A Cisteró, F Borrego. Body and mouthfeel potentiated foods and beverages
containing neohesperidin dihydrochalcone. US Patent No. 5,300,309 (1994).
64. R Foguet, A Cisteró, F Borrego. Use of neohesperidin dihydrochalcone for potentiating
body and mouthfeel of foods and beverages. Eur Patent Specification No.
0 500 977 B1 (1995).
65. L Engels, G Stagnitti. Flavor modifying composition. WO Patent No. 96/17527
(1996).
66. F Borrego, H Montijano. Anwendungsmöglichkeiten des Süssstoffs Neohesperidin
Dihydrochalkon in Arneimitteln. Pharm Ind 57:880–882, 1995.
67. MA Bruna, RJ Miralles, JA Poch, FL Redondo. Compositions for alkalinizing and
energy-boosting drinks. WO Patent No. 96/03059 (Feb. 8, 1996).
68. R Foguet, F Borrego, J Campos, JA Madrid, S Zamora. New feed for cultured fish.
Eur Patent Application No. 0 655 203 A1.
69. MR Gumbmann, DH Gould, DJ Robbins, AN Booth. Toxicity studies of neohesperidin
dihydrochalcone. In: JH Shaw, GG Roussos, eds. Proceedings, Sweeteners and
Dental Caries. Washington, DC: Information Retrieval, 1978, pp 301–310.
70. RP Batzinger, SYL Ou, E Bueding. Saccharin and other sweeteners: Mutagenic
properties. Science 198:944–946, 1977.
71. JP Brown, PS Dietrich, RJ Brown. Frameshift mutagenicity of certain naturally occurring
phenolic compounds in the Salmonella/microsome test: Activation of anthraquinone
and flavonol glycosides by gut bacterial enzymes. Biochem Soc Trans 5:
1489–1492, 1977.
72. JT MacGregor, L Jurd. Mutagenicity of plant flavonoids: Structural requirements
for mutagenic activity in Salmonella typhimurium. Mutation Res 54:297–309,
1978.
73. JB Brown, PS Dietrich. Mutagenicity of plant flavonols in the Salmonella/mammalian
microsome test: Activation of flavonol glycosides by mixed glycosidases from
rat cecal bacteria and other sources. Mutation Res 66:223–240, 1979.