Title: Alternative Sweeteners

356 Olinger and Pepper
50. J Gordon, M Cronin, R Reardon. Ability of a xylitol chewing gum to reduce plaque
accumulation. J Dent Res 69:136.
51. W Edgar. Sugar substitutes, chewing gum and dental caries—a review. Br Dent J
184 (1):29–31, 1998.
52. RJ Feigal, ME Jensen, CA Mensing. Dental caries potential of liquid medications.
Pediatrics 68:416–419, 1981.
53. PE Souney, DA Cyr, JT Chang, AE Kaul. Sugar content of selected pharmaceuticals.
Diabetes Care 6:231–240 (1983).
54. IF Roberts, GJ Roberts. Relation between medicines sweetened with sucrose and
dental disease. BMJ 2:14–16, 1979.
55. PJM Crawford. Sweetened medicine and caries. Pharm J 226:668–669, 1981.
56. HR Muehlemann, A Firestone. Drei neue ‘‘zahnscshonende’’ Präparate. Swiss Dent
3:25–30, 1982.
57. E Kristoffersson, S Halme. Xylitol as an excipient in oral lozenges. Acta Pharm
Fenn 87:61–73, 1978.
58. R Laakso, K Sneck, E Kristoffersson. Xylitol and Avicel pH 102 as excipients
in tablets made by compression and from granulate. Acta Pharm Fenn 91:47–54,
1982.
59. DW Bloch, MA El Egakey, PP Speiser. Verbesserung der Auflösungsgeschwindigkeit
von Hydrochlorothiazid durch feste Dispersionen mit Xylitol. Acta Pharm
Technol 18:177–183, 1982.
60. I Sirenius, VE Krogerus, T Leppaenen. Dissolution rate of p-aminobenzoates from
solid xylitol dispersions. J Pharm Sci 68:791–792, 1979.
61. L Morris, J Moore, J Schwartz. Characterisation and Performance of a New Direct
Compression Excipient for Chewable Tablets: Xylitab, American Association of
Pharmaceutical Scientist Annual Meeting, 1993.
62. JSM Garr, MH Rubinstein. Direct compression characteristics of Xylitol. Inst
Pharm 64:223–226, 1990.
63. F Voirol, R. Etter. Verfahren zur Erzeugung einer Deckschicht auf Tablettenkernen.
German Patent Appl. 29 13 555, 1979.
64. J Sintes, C Escalante, B Stewart, J McCod, L Garcia, Volpe, C Triol. Enhanced
anticaries efficacy of a 0.243% sodium fluoride/10% xylitol/silica dentifrice: 3year
clinical results. Am J Dent 8(5):231–235, 1995.
65. KK Maekinen, E Soderling, I Laeikkoe. Zuckeralkohole (Polyole) als ‘‘aktive’’
Zahnpastenbestandteile. Oralprophylaxe, 9:115–120, 1987.
66. KK Maekinen, E Soederling, H Hurttia, OP Lehtonen, E Luukkala. Biochemical,
microbiologic and clinical comparisons between two dentifrices that contain different
mixtures of sugar alcohols. J Am Dent Assoc 111:745–751, 1985.
67. AA Scheie, O Fejerskov, S Assev, G Roella. Ultrastructural changes in Streptococcus
sobrinus induced by xylitol, NaF and ZnCl 2. Caries Res 23:320–327, 1989.
68. J Arends, J Christoffersen, J Schuthof, MT Smits. Influence of xylitol on demineralization
of enamel. Caries Res 18:296–301, 1984.
69. MT Smits, J Arends. Influence of extraoral xylitol and sucrose dippings on enamel
demineralization in vivo. Caries Res 22:160–165, 1988.
70. M Svanberg, D Birkhed. Effects of dentrifices containing either xylitol and glycerin
or sorbitol on Streptococcus mutans in saliva. Caries Res 25:74–79, 1995.