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Title: Alternative Sweeteners

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68 Bopp and Price<br />

V. ADMIXTURE POTENTIAL<br />

Cyclamate has most frequently been used in combination with saccharin. In the<br />

1950s, it was shown that cyclamate–saccharin mixtures are sweeter than would<br />

be expected from the known sweetness of either component alone and that any<br />

off-taste is minimized with the mixtures (3, 4). About a 10–20% synergism is<br />

observed when cyclamate and saccharin are used together. For example, a combination<br />

of 5 mg saccharin and 50 mg cyclamate in a tabletop sweetener is as sweet<br />

as 125 mg cyclamate alone or 12.5 mg saccharin alone (13). Although the ratio<br />

of cyclamate to saccharin can vary considerably from product to product, the<br />

10:1 mixture is used most frequently. With this combination, each component<br />

contributes about equally to the sweetness of the mixture because saccharin is<br />

about 10 times sweeter than cyclamate.<br />

More recently, numerous patents have described the use of cyclamate in<br />

combination with aspartame or aspartame and saccharin (e.g., 18, 19). Applications<br />

have also been reported for cyclamate in combination with acesulfame-K<br />

and other sweeteners (20). If and when cyclamate is again approved for use in<br />

the United States, it would undoubtedly be used primarily in combination with<br />

other more potent sweeteners because no one sweetener appears to meet all the<br />

technological requirements, and mixtures of sweeteners generally appear to offer<br />

improved taste.<br />

VI. TECHNICAL QUALITIES<br />

Cyclamate has a number of technical qualities that make it a good alternative<br />

sweetener (13, 17, 21). It is noncaloric and noncariogenic. Although its relative<br />

sweetness is less than that of saccharin or aspartame, its sweetening power is<br />

adequate, especially when used in combination with other more intense sweeteners.<br />

Cyclamate has a favorable taste profile and does not leave an unpleasant<br />

aftertaste at normal use concentrations. It is better than sugar in masking bitterness,<br />

and it enhances fruit flavors. Cyclamate is compatible with most foods and<br />

food ingredients, as well as with natural and artificial flavoring agents, chemical<br />

preservatives, and other sweeteners. Its solubility is more than adequate for most<br />

uses, and at normal concentrations it does not change the viscosity or density of<br />

solutions. The stability of cyclamate is excellent, at both high and low temperatures,<br />

over a wide pH range, and in the presence of light, oxygen, and other food<br />

chemicals. Cyclamate is nonhygroscopic and will not support mold or bacterial<br />

growth. However, like most noncaloric sweeteners, cyclamate does not provide<br />

the bulk, texture, or body associated with sugar.

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