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Abstract Book - 3rd International Symposium on Medicinal Plants ...

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ingredient were developed. Nano-niosomes c<strong>on</strong>taining Allium sativa encapsulated with sorbitan<br />

m<strong>on</strong>ooleate (0.3%) and PEG400 (1%) has the average particle size of 171 nm and exhibited<br />

excellent stability after heating-cooling 6 cycles, at room temperature, and at 40 °C for 1 m<strong>on</strong>th.<br />

Particle size of selected formulati<strong>on</strong> in all tested c<strong>on</strong>diti<strong>on</strong>s was changed within the range of ± 7.07<br />

%. Allium sativum extract exhibited the highest lipolysis activity. Therefore, it was selected to be<br />

the active ingredient in nano-niosome for cellulite treatment. Nano-niosomes c<strong>on</strong>taining Allium<br />

sativum extract encapsulated with sorbitan m<strong>on</strong>ooleate (0.3%) and PEG400 (1%) has the particle<br />

size lower than 200 nm and exhibited excellent stability after heating-cooling 6 cycles and room<br />

temperature of 40 °C for 1 m<strong>on</strong>th.<br />

Key words: Cellulite treatment, herbal extracts, lipolysis, nano formulati<strong>on</strong>.<br />

1.90 Studies <strong>on</strong> the Antioxidant and Antibacterial Activities of Swertia<br />

chirata (Bush ham) plant Extracts Using in Vitro Models.<br />

Syed Ali Raza Naqvi 1 ., Zulfiqar, A. K 1 ., Sohail, A. S 2 ., Muhammad, Y 3 ., Qurat-<br />

Ul-A 1 ., and Nasir M 4 .<br />

1 Department of Chemistry, Government College University. 2 Department of Chemistry, COMSATS<br />

institute of informati<strong>on</strong> technology. 3 Interdisciplinary Research Center in Biomedical Materials,<br />

COMSATS Institute of Informati<strong>on</strong> Technology. 4 Department of Allied Health Sciences, University<br />

of Health Sciences, Lahore-PAKISTAN<br />

<str<strong>on</strong>g>Abstract</str<strong>on</strong>g>: Like many other plants and herbs, Swertia charata has also been used for treating<br />

different infecti<strong>on</strong>s and diseases particularly liver disorder. Anti-diseased functi<strong>on</strong> of most of the<br />

plants or herbs extracts has been associated with its antioxidant and anti bacterial potential. This<br />

study was performed to explore the antioxidant and antibacterial activity of the Swertia charata<br />

(Bush ham) endemic to the central Punjab of Pakistan. This was d<strong>on</strong>e by measuring possible<br />

c<strong>on</strong>stituents resp<strong>on</strong>sible for its anti-oxidant activity e.g. DPPH radical scavenging potential, total<br />

phenolic c<strong>on</strong>tents, reducing power, total flav<strong>on</strong>oide c<strong>on</strong>tents, and antibacterial power against four<br />

different strains of gram positive and gram negative bacteria. The antioxidant activity of methanolic<br />

and ethanolic extract of plant using DPPH model showed 84.32% and 82.54% respectively. Total<br />

phenolic c<strong>on</strong>tents of both extracts showed 2.565g (GAE)/100g and 1.612g (GAE)/100g was noted,<br />

respectively. Measured values of all these c<strong>on</strong>stituents explain str<strong>on</strong>g anti-oxidant activity of the<br />

plants. HPLC analysis of plant extracts exhibit promising c<strong>on</strong>centrati<strong>on</strong> of phenolic c<strong>on</strong>tents.<br />

Further the antibacterial activity indicates best possible use of this plant extract against infectious<br />

diseases in additi<strong>on</strong> to diseases associated with oxidati<strong>on</strong> process.<br />

Key Words: Antioxidants, free radical, HPLC, antibacterial activity, total phenolics, swertia<br />

charata.<br />

1.91 Chemical compositi<strong>on</strong> of the Essential oils of Daucus reboudii and their<br />

Antibacterial Activity<br />

Tahar Smaili 1,2 ., Amar Z 2 ., Khellaf R 1 ., Ghadbane M 1 ., Abdelwahab B 1 ., P. C 3 .<br />

and Guido F 3 .<br />

1 Département de Sciences de la Nature et de la Vie , Faculté de Sciences, Université de M'sila ,<br />

28000 M'sila. 2 Laboratory of Biomolecules and Plant Breeding, Life Science and Nature<br />

Department, Faculty of Exact Science and Life Science and Nature, University of Larbi Ben Mhidi<br />

Oum El Bouaghi, Algeria. 3 Dipartimento di Scienze Farmaceutiche, Sede di Chimica Bioorganica e<br />

Biofarmacia, University of Pisa, Via B<strong>on</strong>anno 33, 56126 Pisa, Italy<br />

<str<strong>on</strong>g>Abstract</str<strong>on</strong>g>: The essential oils obtained from aerial parts of Daucu reboudii Coss. (Apiaceae)<br />

which is endemic to north Africa collected from Nati<strong>on</strong>al Park of Gouraya (Bejaïa, Algeria) were<br />

analyzed by GC/MS. 28 compounds were identified accounting for 97.8% of the total oil, the result<br />

48

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