Abstract Book - 3rd International Symposium on Medicinal Plants ...

Acetone) from Spirulina platensis was examined. The algal extracts were tested in vitro for their
antifungal effects using Agar well diffusion method and Paper disc diffusion method and
concentration from 250ppm up to 7000 ppm was taken and observed all these bacteria showed
inhibition in growth by these extracts. During GC-MS analysis and NMR analysis the effective
antifungal compound was identified as fatty acid compound associated with the antifungal
properties.
Key words: Algal extracts, diffusion, fungi, growth, phytomedicines, Spirulina platensis.
1.96 Antibacterial Activity of Tea, Origano and Ginger Extracts
Zerroug Mohamed Mihoub 1 , Bouriche Hamama 2 , and Senator Abderrahmne 2
1 Laboratory of Applied Microbiology, Faculty of Natural and Life Sciences, University Ferhat Abbas
of Sétif. 2 Laboratory of Applied Biochemistry, Faculty of Natural and Life Sciences, University
Ferhat Abbas of Sétif, Algeria
<strong>Abstract</strong>: Natural drug resistance to human pathogenic bacteria has been commonly reported
from all over the world. This fact urged to discover new antimicrobial compounds with diverse
chemical structures and novel mechanisms of action. Many plants which are used in traditional
medicine are considered as a source of antimicrobial compounds. In this study, the antibacterial
activity of aqueous extracts obtained by infusion or decoction of tea (Camellia sinsnsis), origano
(Origanum glandulosum) and ginger (Zingiber officinalis) were tested against E. coli MC 4100
(NCTC 9002), Pseudomonas diminutus (NCTC 8545) and Paracoccus paratrophus. Bacterial
suspensions (100 µl) were spread on tryptone soya agar (TSA) medium. Plant extracts (10 µl)
were applied to discs of filter paper and placed on agar plates containing the microorganisms. The
plates were incubated at 37°C for 48h. After incubation the zones of inhibition around the discs
was measured. Results showed that the plant extracts inhibited bacterial growth, tea extract
inhibited the growth of the three bacteria with zones of inhibition of 10 mm for E. coli, Paracoccus
paratrophus and 11 mm for Pseudomonas diminutus. Ginger infusion gave zones of inhibition
against E. coli and Pseudomonas diminutus of 10 mm. In contrast, origano infusion inhibited only
E. coli by 9 mm. Tea decoction inhibited the growth of E. coli and Paracoccus paratrophus with 11
and 9 mm, respectively. While ginger and origano extracts had no antibacterial effect.
Key words: Antibacterial activity, ginger, origano, tea.
1.97 Neuroprotective Effect of Curcuma Longa Administrated with Pepper
nigrum Against Aluminium Neurotoxicity and Alzheimer’s Disease
(Experimental Studies in Mice)
ZERROUKI Khayra, and DJEBLI Noureddine
Department of biology, Faculty of exact science and natural and life science, University of
Mostaganem, Mostaganem-Algeria
<strong>Abstract</strong>: Chemicals with neurotoxic effects are found to be very different, citing the aluminum
which can cause serious consequences, not only on the nervous system but also on other organs
(liver, kidneys, bones ...) The presence of aluminum in the internal medium (blood) can take only a
few hours, but with sub-acute exposure to chronic, this metal can be stored in several tissues
(liver, bone, cartilage, nervous ... ) causing serious complications can go to the molecular level and
resulted in tumor diseases and irreversible damages. Currently, the toxicity of aluminum is well
established in the animal laboratory, and the neurotoxic effect is studied by means of behavioral
tests, memory tests, histological and biological analysis. Several means were considered to fight
against this severe health problem, including, herbal medicine which is based on the effectiveness
of the antioxidant effect on lesions induced by metals. Curcuma longa is a powerful antioxidant
used to reduce the damage causes by aluminum; it shows a protective effect against neurotoxicity,
a large effect against antioxidative stress inhibiting the reactions cascade of neurofibrillary tangles,
it‟s classed between therapeutic agents fight against neurodegenerative disorders and Alzheimer's
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