Abstract Book - 3rd International Symposium on Medicinal Plants ...

disease induced by AlCl3 on the pyramidal cells in cerebral cortex and hippocampus of albino
mice; but it‟s less bioavailability and it‟s fast eliminated by the liver detoxification pathways, obliged
there administration with piperine exist in Pepper nigrum, inhibitor of the key enzyme involved in
detoxification, which helps maintain a high rate of curcumin (Curcuma longa) longer. Our aim is
realized by means of two experiences with a different exposition of albino mice; sub acute and
chronic exposure with a different manner (Oral and IP) on Curcumin with a Pepper as a fixative of
absorption and AlCl3.
Key words: Aluminum, alzheimer disease, antioxidant, Curcuma longa, neurotoxicity.
1.98The Search of Plants with Expressed Theurapeutic Activity among the
Cabbage Family
Zinchenko, Iryna., Tartynska, G., Kolisnyk, Y., and Kyslychenko, V.
National University of Pharmacy, Kharkiv, Ukraine
<strong>Abstract</strong>: For centuries plants have been used by people all over the world due to their healing
properties. Nowadays, when the pharmaceutic industry proposes more and more effective drugs,
the usage of medicinal plants doesn‟t lose its actuality. The plants from the Brassicaceae family
are a good source of natural antioxidants due to the high levels of carotenoids, tocopherols,
phenolic compounds, and ascorbic acid, which help to protect the human body against damage by
reactive oxygen. The consumption of Brassica vegetables has been related to the reduction of the
chronic diseases risk, and also diseases of cardiovascular system and cancer. In addition, plants
from the Brassicaceae family are very nutritive, providing nutrients and health-promoting
phytochemicals such as vitamins, carotenoids, fiber, soluble sugars, minerals, glucosinolates and
phenolic compounds. Taking into account all the above mentioned advantages of these plants, the
study of the Brassicaceae family representatives as prospective sources of biologically active
compounds with expressed theurapeutic activity is carried out at the department of the chemistry
of natural compounds of the National University of Pharmacy (Kharkiv, Ukraine). The shepherd‟s
purse (Capsella bursa-pastoris) herb is used in official medicine as a styptic agent in uteral,
intestinal, nephritic, and pulmonary bleedings. The plant is also known to possess antibacterial
and antioxidant properties. Field penny-cress (Thlaspi arvense) is an unofficial plant but it has
been widely used in folk medicine as a styptic, cytostatic remedy, and which also has slight
expectorant properties. It is used in cardiovascular, gastrointestinal diseases, it is also
recommended in ovaritis and sexual impotence in men. The study carried out at the departments
of the chemistry of natural compounds and pharmacology of the National University of Pharmacy
has shown the field penny-cress to possess prostate-protective, anti-inflammatory and
antimicrobial properties. Due to the presence of a large plant material base our attention was
attracted to tyfon (Brassica campestris var. chinensis DC × Brassica rapa L.) – a hybrid of Chinese
cabbage and turnip. The study of its chemical composition has shown the presence of such
groups of biologically active compounds as sugars, polysaccharides, vitamins, organic acids,
flavonoids, hydroxycinnamic acids, polyphenols, and steroidal saponins. At present the tyfon herb
extract is being worked out which has anabolic properties. From all the above mentioned it can be
concluded that these representatives of the Brassicaceae family are a prospective source of new
phytoremedies.
Key words: Cabbage, plant, theurapeutic activity, tyfon herb.
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