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This is a relatively low-risk treatment that — especially
compared to chemo and radiation — has negligible disadvantages.
In many cases, a simple enucleation (just cutting out
the tumor with a safe margin around it) is enough and leaves
no residual side-effects.
now, about this specific case:
Jobs had many favorable factors that indicate an early
surgical treatment could have been curative.
• Mr. Jobs said himself that they caught the tumor early.
early in GeP-neTs means in many cases that surgically
removing the primary tumor without additional removal
of organs is a curative with a low chance or recurrence.
• The tumor was located at a relatively clement site, the
pancreas.
• The tumor was allegedly an insulinoma, one of the best
treatable subtypes of GeP-neTs.
• The tumor was probably well-differentiated. Mr. Jobs
spoke of a hormonal imbalance, this points to a tumor
that keeps its endocrine function, which is an general
indicator of good differentiation. Well-differentiated tumors
are less prone to metastasize and grow rapidly.
See table linked to below for a comprehensive illustration of
the numbers I'm referring to, I chose an article from The Annals
of Oncology as a source as it's one of the few papers freely
accessible for everyone interested to read the full article: http://
annonc.oxfordjournals.org/content/21/9/1794.
. . . but not treating the most innocent cancer can still
cause it to go seriously bad.
I'm currently reviewing hundreds of colon cancer cases,
and about 25% of them start with a patient that comes with
a history of polyps. Polyps are small benign little growths in
the lining of the intestine. They are absolutely harmless at
first, yet slowly but surely, over years, they lose more and more
of the above mentioned "differentiation" and some eventually
turn to a malign colon cancer.
In fact, it is supposed that all colon cancers start as a polyp.
These 25% had polyps removed, but were unlucky enough
that between two colonoscopies, some other polyp found the
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