INTRODUCCIÓN: REVISIÓN CRITICA DEL PROBLEMA

RESULTADOS
following exceptions. First, ischaemic patients were predominantly males with
depressed LVEF (P = 0.012). Second, the number of patients with diabetes
mellitus and hyperlipidaemia was higher in the group with ischaemic aetiology,
although statistical significance was not reached for these parameters. Statistically
significant differences were not observed for age, arterial hypertension, functional
class, renal function or other variables.
The average concentration of sRAGE was 1236 pg/mL. Mean serum fluorescent
AGE, and glycated albumin levels are also shown in Table 1. Relationships
between plasma sRAGE concentration and fluorescent AGE, fructosamine,
glycated haemoglobin and glycated albumin levels are shown in Table 2.
Fluorescent AGE was directly correlated with fructosamine (r = 0.310, P = 0.032)
and glycated albumin (r = 0.212, P = 0.031), but not with glycated haemoglobin (r
= 0.124, P = 0.317) or fasting glycaemia (r = 0.089, P = 0.377).
Fructosamine
Glycated
haemoglobin
Glycated
albumin
Fluorescent
AGE
sRAGE
TABLE 2. Correlations between glycation parameters.
r
p
r
p
r
p
r
p
r
p
Fructosamine
0.710
0.000
Glycated
haemoglobin
0.710
0.000
Glycated
albumin
0.147
0.319
Fluorescent
AGE
0.310
0.032
0.124
0.317
sRAGE
0.358
0.012
0.233
0.057
0.147 0.186 0.212 0.045
0.319 0.131 0.031 0.654
0.310
0.032
0.124
0.317
0.212
0.031
0.358 0.233 0.145 0.181
0.012 0.057 0.654 0.067
0.181
0.067
By contrast, concentrations of fluorescent AGE, glycated albumin and glycated
haemoglobin were higher in the diabetic group (70.56±3.46 vs. 62.70±2.49 AU, P
= 0.066; 25.63±2.31 vs. 18.86±1.27 ng/mL, P = 0.013; 7.30±0.25 vs. 5.81±0.11%,
P < 0.001, respectively). There were no differences in serum sRAGE levels
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