INTRODUCCIÓN: REVISIÓN CRITICA DEL PROBLEMA

CAPÍTULO IV
c) Correlation between the receptor of advanced glycation end products–
advanced glycation end products system and heart failure symptoms
A direct correlation was observed
between sRAGE levels and NYHA
functional class for dyspnoea (Figure
4). Likewise, using the cut-off point
determined in the ROC analysis to
predict ischaemic aetiology, we
more frequently observed higher
functional classes in the group of
patients with sRAGE . 986.0 pg/mL
(Table 3). Neither fluorescent AGE
nor glycated albumin had a
statistically significant association
with severity of dyspnoea, although
fluorescent AGE showed an
increasing trend with functional
class. With respect to brain
natriuretic peptide (BNP), patients
with values