INTRODUCCIÓN: REVISIÓN CRITICA DEL PROBLEMA

CAPÍTULO IV
116
TABLE 3. Clinical characteristics of high and low sRAGE patients groups
Variables
Low sRAGE
(1220 pg/mL)
(n = 30)
p value
DEMOGRAPHIC FACTORS
Age (years) 68.9 ± 1.4 71.30 ± 1.8 0.370
Sex (male/female) 67.1 % / 32.9 % 63.3 % / 36.7 % 0.712
Medium blood pressure (mmHg) 94.6 ± 1.7 93.9 ± 2.7 0.815
IMC (kg/m 2 ) 28.5 ± 0.6 27.4 ± 1.2 0.360
CARDIOVASCULAR RISK FACTORS
Arterial Hypertension 65.8 % 60.0 % 0.580
Hyperlipidemia 62.5 % 56.7 % 0.582
Diabetes mellitus 35.6 % 36.7 % 0.920
Smokers 8.2 % 6.7 %
Ex-smokers 34.2 % 26.7 %
ISCHEMIC ETIOLOGY AND SEVERITY
0.690
Ischemic 21.9 % 50.0 % 0.005
One damaged vessel
Two damaged vessels
Three damaged vessels
NYHA I
NYHA II
NYHA III
68.8 %
18.8 %
12.5 %
FUNCTIONAL CLASS (NYHA)
17.4 %
66.7 %
15.9 %
6.70 %
53.3 %
40.0 %
3.3 %
63.3 %
33.3 %
0.002
0.046
EKG
Rhythm (sinusal/non) 70.8 % / 29.2 % 33.3 % / 66.7 % 0.001
ECHOCARDIOGRAPHY
Depressed LVEF 77.5 % 72.4 % 0.592
Left ventricular hipertrophy 52.5 % 44.4 % 0.322
Left ventricular dilatation 60.3 % 66.7 % 0.643
Left atrial dilatation 84.4 % 100 % 0.029
ANALITIC PARAMETERS
Glucose (mg/dL) 116.6 ± 3.6 133.6 ± 12.0 0.185
Fructosamine (mg/dL) 248.5 ± 14.4 289.9 ± 16.9 0.106
Glycated haemoglobin (%) 6.5 ± 0.2 7.0 ± 0.3 0.178
Glycated albumin (ng/mL) 21.3 ± 1.5 21.25 ± 1.84 0.964
Fluorescent AGEs (AU) 63.1 ± 2.3 71.52 ± 3.97 0.061
Haemoglobin (g/dL) 13.5 ± 0.2 12.5 ± 0.23 0.002
Creatinine (mg/dL) 1.10 ± 0.03 1.18 ± 0.06 0.179
Estimated glomerular filtrate (ml/min) 61.51 ± 2.15 52.50 ± 2.77 0.054
Cystatine (mg/L) 0.98 ± 0.05 1.19 ± 0.10 0.020
NTproBNP > 400 pg/mL 75.4% 100% 0.009
LDL (mg/dL) 112.83 ± 3.73 108.53 ± 8.05 0.581
HDL (mg/dL) 44.63 ± 2.42 43.18 ± 3.34 0.738
Triglicerides (mg/dL) 120.01 ± 7.57 104.32 ± 10.80 0.262
TREATMENT
B-blockers 89.0 % 80.0 % 0.224
ACE inhibitors/ARA 93.2 % 96.7 % 0.778
Espironolactone 61.6 % 70.0 % 0.422
Diuretics 79.5 % 83.3 % 0.218
Antiplatelets 46.6 % 30.0 % 0.618
Nitrates 12.2 % 26.7 % 0.075
Statins 45.2 % 50.0 % 0.658
Oral antidiabetic drugs 28.8 % 20.0 % 0.358
Insulin 6.8 % 16.7 % 0.126
Abbreviations as in Table 1