Dimorfismo sexual en enfermedades autoinmunes - Ibáñez&Plaza ...

Dimorfismo sexual en enfermedades autoinmunes: nuevos desafíos en el estudio de la autoinmunidad · Reportaje
in humans. Am J Reprod Immunol. 2004;
52:19-26.
11.McMurray RW, Suwannaroj S, Ndebele K,
Jenkins JK. Differential effects of sex steroids
on T and B cells: modulation of cell
cycle phase distribution, apoptosis and
bcl-2 protein levels. Pathobiology. 2001;
69:44-58.
12.Butterworth M, McClellan B, Allansmith
M. Influence of sex in immunoglobulin levels.
Nature. 1967; 214:1224-1225.
13.Giglio T, Imro MA, Filaci G, Scudeletti M,
Puppo F, De Cecco L, et al. Immune cell
circulating subsets are affected by gonadal
function. Life Sci. 1994; 54:1305-
1312.
14.Nelson JL. Microchimerism and autoimmune
disease. N Engl J Med. 1998;
338:1224-1225.
15.McCombe PA, Greer JM, Mackay IR. Sexual
dimorphism in autoimmune disease.
Curr Mol Med. 2009; 9:1058-1079.
16.McNallan KT, Aponte C, el-Azhary R, Mason
T, Nelson AM, Paat JJ, et al. Immunophenotyping
of chimeric cells in localized
scleroderma. Rheumatology (Oxford).
2007; 46:398-402.
17.Loubiere LS, Lambert NC, Flinn LJ, Erickson
TD, Yan Z, Guthrie KA, et al. Maternal
microchimerism in healthy adults in
lymphocytes, monocyte/macrophages
and NK cells. Lab Invest. 2006;
86:1185-1192.
18.Artlett CM, Smith JB, Jimenez SA. Identification
of fetal DNA and cells in skin lesions
from women with systemic sclerosis.
N Engl J Med. 1998; 338:1186-1191.
19.Artlett CM. Microchimerism and scleroderma:
an update. Curr Rheumatol Rep.
2003; 5:154-159.
20.Renne C, Ramos Lopez E, Steimle-Grauer
SA, Ziolkowski P, Pani MA, Luther C, et al.
Thyroid fetal male microchimerisms in
mothers with thyroid disorders: presence
of Y-chromosomal immunofluorescence
in thyroid-infiltrating lymphocytes is
more prevalent in Hashimoto's thyroiditis
and Graves' disease than in follicular
adenomas. J Clin Endocrinol Metab.
2004; 89:5810-5814.
21.Friedrich N, Schwarz S, Thonack J, John U,
Wallaschofski H, Volzke H. Association
between parity and autoimmune thyroiditis
in a general female population. Autoimmunity.
2008; 41:174-180.
22.Bülow PI, Laurberg P, Knudsen N, Jørgensen
T, Perrild H, Ovesen L, et al. Lack of
association between thyroid autoantibodies
and parity in a population study argues
against microchimerism as a trigger
of thyroid autoimmunity. Eur J Endocrinol.
2006; 154:39-45.
23.Artlett CM, Ramos R, Jiminez SA, Patterson
K, Miller FW, Rider LG. Chimeric cells
of maternal origin in juvenile idiopathic
inflammatory myopathies. Childhood
Myositis Heterogeneity Collaborative
Group. Lancet. 2000; 356:2155-2156.
24.Willer CJ, Herrera BM, Morrison KM, Sadovnick
AD, Ebers GC. Association between
microchimerism and multiple sclerosis
in Canadian twins. J Neuroimmunol.
2006; 179:145-151.
25.Scofield RH, Bruner GR, Namjou B, Kimberly
RP, Ramsey-Goldman R, Petri M,
et al. Klinefelter's syndrome (47,XXY) in
male systemic lupus erythematosus
patients: support for the notion of a
gene-dose effect from the X chromosome.
Arthritis Rheum. 2008; 58:2511-
2517.
26.Cooney CM, Bruner GR, Aberle T, Namjou-
Khales B, Myers LK, Feo L, et al.
46,X,del(X)(q13) Turner's syndrome women
with systemic lupus erythematosus
in a pedigree multiplex for SLE. Genes
Immun. 2009; 10:478-481.
27.Lyon MF. Gene action in the X-chromosome
of the mouse (Mus musculus L.). Nature.
1961; 190:372-373.
28.Grahn RA, Lemesch BM, Millon LV, Matise
T, Rogers QR, Morris JG, et al. Localizing
the X-linked orange colour phenotype
using feline resource families. Anim Genet.
2005; 36:67-70.
29.Carrel L, Willard HF. X-inactivation profile
reveals extensive variability in X-linked
gene expression in females. Nature.
2005; 434:400-404.
30.Gartler SM, Goldman MA. Biology of the X
chromosome. Curr Opin Pediatr. 2001;
13:340-345.
31.Gabrielli A, Avvedimento EV, Krieg T. Scleroderma.
N Engl J Med. 2009; 360:1989-
2003.
32.Sakkas LI, Xu B, Artlett CM, Lu S, Jimenez
SA, Platsoucas CD. Oligoclonal T cell expansion
in the skin of patients with
systemic sclerosis. J Immunol. 2002;
168:3649-3659.
33.Invernizzi P, Miozzo M, Selmi C, Persani L,
Battezzati PM, Zuin M, et al. X chromosome
monosomy: a common mechanism
for autoimmune diseases. J Immunol.
2005; 175:575-578.
34.Ozbalkan Z, Bagislar S, Kiraz S, Akyerli
CB, Ozer HT, Yavuz S, et al. Skewed X
chromosome inactivation in blood cells
of women with scleroderma. Arthritis
Rheum. 2005; 52:1564-1570.
35.Uz E, Loubiere LS, Gadi VK, Ozbalkan Z,
Stewart J, Nelson JL, et al. Skewed X-
chromosome inactivation in scleroderma.
Clin Rev Allergy Immunol. 2008;
34:352-355.
36.Chabchoub G, Uz E, Maalej A, Mustafa
CA, Rebai A, Mnif M, et al. Analysis of
skewed X-chromosome inactivation in
females with rheumatoid arthritis and
autoimmune thyroid diseases. Arthritis
Res Ther. 2009; 11:R106.
37.Ozcelik T, Uz E, Akyerli CB, Bagislar S,
Mustafa CA, Gursoy A, et al. Evidence
from autoimmune thyroiditis of skewed
X-chromosome inactivation in female
predisposition to autoimmunity. Eur J
Hum Genet. 2006; 14:791-797.
38.Invernizzi P, Pasini S, Selmi C, Miozzo M,
Podda M. Skewing of X chromosome inactivation
in autoimmunity. Autoimmunity.
2008; 41:272-277.
39.Knudsen GP, Harbo HF, Smestad C, Celius
EG, Akesson E, Oturai A, et al. X chromosome
inactivation in females with multiple
sclerosis. Eur J Neurol. 2007;
14:1392-1396.
40.Altshuler D, Daly MJ, Lander ES. Genetic
mapping in human disease. Science.
2008; 322:881-888.
41.Burkhardt J, Petit-Teixeira E, Teixeira VH,
Kirsten H, Garnier S, Ruehle S, et al. Association
of the X-chromosomal genes
TIMP1 and IL9R with rheumatoid arthritis.
J Rheumatol. 2009; 36:2149-2157.
42.Dubois PC, Trynka G, Franke L, Hunt KA,
Romanos J, Curtotti A, et al. Multiple
common variants for celiac disease influencing
immune gene expression. Nat
Genet. 2010; 42:295-302.
43.Barrett JC, Clayton DG, Concannon P,
Akolkar B, Cooper JD, Erlich HA, et al. Genome-wide
association study and metaanalysis
find that over 40 loci affect risk
of type 1 diabetes. Nat Genet. 2009;
41:703-707.
Cuadernos de Autoinmunidad
9