thesis

248
A
20 mV
B
C
D
-15 mV
threshold threshold threshold
-40 mV
-32 mV
-50 mV
-34 mV
-50 mV
0 mV/ms
rate of depolarization
5 mV/ms
Figure 9.6 – Spike threshold measurements in a stellate cell of the cochlear nucleus.
A. Compensated voltage trace of a stellate cell in response to an injected fluctuating current.
Spike thresholds are measured as the membrane potential when the first derivative exceeds 1 V/ s
(dots). B. Spike threshold as a function of depolarization rate in the 10 ms preceding each spike,
when the trace is not compensated (dashed line : linear regression). C. Same relationship in the
bridge compensated trace. D. Same relationship in the trace compensated with our method.