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Table 4.3.4 List of included studies with DIAGNOdent.<br />

Author<br />

Year,<br />

reference<br />

Country<br />

Type of<br />

study<br />

Blinding<br />

Number<br />

of<br />

observers<br />

Observer<br />

reliability<br />

Population<br />

Caries<br />

prevalence<br />

and type<br />

of lesions<br />

Clinical studies<br />

Primary teeth<br />

Rocha et al<br />

2003 [4]<br />

Brazil<br />

Occlusal<br />

Angnes et al<br />

2005 [5]<br />

Brazil<br />

Reis et al<br />

2006 [6]<br />

Brazil<br />

Validity,<br />

reliability<br />

Yes 2 Kappa<br />

Intra mean:<br />

66%<br />

Inter mean:<br />

61%<br />

10–11 yrs,<br />

molars<br />

under exfoliation<br />

or<br />

extracted<br />

for orthodontic<br />

reasons<br />

Validity Partly 2 Kappa: 53% Adult<br />

volunteers,<br />

3rd molars<br />

for extraction<br />

Validity Partly 2 Kappa: 57%<br />

In vivo/<br />

in vitro<br />

Intra: 0.28<br />

Inter: 0.28<br />

Adult<br />

volunteers,<br />

3rd molars<br />

for extraction<br />

21 (42%) sound<br />

16 (32%) D1<br />

6 (12%) D2<br />

5 (10%) D3<br />

2 (4%) D4<br />

20 (18%) sound<br />

24 (22%) D1<br />

50 (45%) D2<br />

14 (13%) D3<br />

2 (2%) D4<br />

20 (18%) sound<br />

24 (22%) D1<br />

50 (45%) D2<br />

14 (13%) D3<br />

2 (2%) D4<br />

Studies on extracted teeth<br />

Occlusal<br />

Kordic et al<br />

2003 [3]<br />

Switzerland<br />

Validity Yes 4 Kappa:<br />

60–75%<br />

10–38 yrs,<br />

premolars<br />

and molars<br />

21% sound<br />

61% enamel<br />

18% dentine<br />

CI = Confidence interval; D1 = Enamel caries; D2 = Caries to the enamel-dentine<br />

junction; D3 = Caries reaching not more than half of the dentine; D4 = Caries reaching<br />

more than half of the dentine; NPV = Negative predictive value; PPV = Positive predictive<br />

value; ROC = Receiver operating characteristic; SEM = Scanning electron microscope;<br />

Se = Sensitivity; Sp = Specificity<br />

182<br />

Karies – diagnostik, riskbedömning och icke-invasiv behandling

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