Fulltext - SBU

Predictor
variables
Validating
criteria
Statistical
methods
Results
Sensitivity
and specificity
Study
quality and
relevance
Comments
Oral hygiene (gingival
status), salivary
secretion and buffer,
MS, LB in saliva
>0 new
caries lesion
Proportion
high risk:
Not stated
Se, Sp,
PPV, NPV
Best single predictor
MS
Se: 41%; Sp: 83%
Best combination
of predictors
Gingival status + MS
Se: 53%; Sp: 74%
Low
Small
sample not
described.
Bias from
treatment
Salivary secretion
and buffer did not
improve the model
Baseline dmfs,
MS in saliva
>2 dmfs or
3–4 dmfs,
≥5 dmfs
Proportion
high risk:
36%
Se, Sp,
PPV, NPV
Best for ≥5 dmfs
increment and high
MS group at baseline
Se: 72%; Sp: 72%;
PPV: 0.34; NPV: 0.93
Low
Large dropout.
Heterogeneous
sample
“Caries activity”;
pH assessment;
Cariostat
Caries prevalence
at baseline
MS in saliva; single
or repeated
≥1 new
lesion
Proportion
high risk:
50%
>2 new dfs
Proportion
high risk:
13–28%
Se, Sp,
PPV, NPV
Se, Sp,
PPV, NPV
18–36 months
Se: 61%; Sp: 67%;
PPV: 81%; NPV: 43%
F-exposure influenced
Se and Sp.
Combined baseline
caries and MS: Low
F-exposure best
Se: 65%; Sp: 86%
No improvement
from repeated MStests
Low
Sampling
unclear.
Attrition
unclear
Low
Incomplete
data reported
filled teeth (permanent teeth); LB = Lactobacilli; MS = Mutans streptococci;
NPV = Negative predictive value; NS = Not significant; OR = Odds ratio; PPV = Positive
predictive value; RR = Relative risk; Se = Sensitivity; Sp = Specificity; WHO = World
Health Organization
KAPITEL 5 • Riskbedömning
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