Fulltext - SBU

Predictor
variables
Validating
criteria
Statistical
methods
Results*
Sensitivity and
specificity
Study
quality and
relevance
Comments
Repeated salivary MS
0 vs 1–3, 0–1 vs 2–3,
0–2 vs 3 positive
tests
Fluoride intake,
sucrose intake
plaque
≥1 new dft
or DFT
If exfoliated
at follow-up:
counted as
caries
Only
caries-free
at baseline
included
Se, Sp,
PPV, NPV
Modest improvement
of MS multiple
tests
0 vs 1–3 positive
tests
Se: 50%; Sp: 80%;
PPV: 0.59; NPV:
0.74
Low F, high plaque
Se: 57%; Sp: 94%
Low
Only cariesfree
included.
Bias from
study design
≥1 incipient lesion
or buccal or lingual
surfaces
LB>10 5 CFU/ml
saliva
Yeasts ≥5 CFU/ml
Saliva salivary buffer
capacity: pH ≤5 and
combinations of
these
Age ≤9:
2–3 new
DMFS
Age ≥10:
4–5 new
DMFS
Proportion
high risk:
Median value
(value not
stated)
Se, Sp, log
regression
Incipient lesions (inc)
Se: 52%; Sp: 87%
Combinations
Inc and/or LB +
yeasts
Se: 67%; Sp: 76%
Inc and/ or LB +
yeasts
Se: 70%; Sp: 71%
Salivary buffering
Se: 63%; Sp: 69
Accuracy max 0.77
Low
Very cariesactive
children;
open cavities
common; not
applicable to
populations
of today
Salivary buffering;
2 levels:
pH ≤4 and pH ≤5
≥3 new
DMFS
Proportion
high risk:
Varying
Se, Sp
Best for pH ≤5
at age ≤9 yrs
Se: 58% girls;
52% boys
Sp: 64% girls;
63% boys
Same
material as
Pienihäkkinen
1987 [44].
Important
confounders
not included
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