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Fulltext - SBU

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Predictor<br />

variables<br />

Validating<br />

criteria<br />

Statistical<br />

methods<br />

Results*<br />

Sensitivity and<br />

specificity<br />

Study<br />

quality and<br />

relevance<br />

Comments<br />

MS in fissures<br />

and in plaque<br />

≥1 DMFS in<br />

fissures 1st<br />

permanent<br />

molars<br />

Proportion<br />

high risk:<br />

28%<br />

Se, Sp<br />

MS low vs MS high<br />

Se: 50%; Sp: 82%;<br />

PPV: 0.29; NPV:<br />

0.92<br />

Low<br />

Bias from<br />

treatment:<br />

24% fissure<br />

sealed. No<br />

reproducibility<br />

test<br />

MS, LB in saliva<br />

≥3 new<br />

lesions<br />

(including<br />

initial)<br />

≥10 5 LB<br />

≥10 5 MS<br />

Proportion<br />

high risk:<br />

Around 20%<br />

Se, Sp,<br />

PPV, NPV<br />

8 yr-olds<br />

MS alone<br />

Se: 67%; Sp: 74%<br />

LB alone<br />

Se: 44%; Sp: 86%<br />

MS and LD<br />

Se: 72%; Sp: 67%<br />

Low<br />

Too short<br />

follow-up for<br />

permanent<br />

teeth. Incomplete<br />

data<br />

reporting<br />

MS, sanguis, mitior,<br />

salivarius, LB >1%<br />

MS in pooled plaque<br />

was used as cut-off<br />

>0 new DFS<br />

Proportion<br />

high risk:<br />

49%<br />

Se, Sp,<br />

PPV, NPV<br />

Only MS was statistically<br />

significantly<br />

associated with<br />

caries increment<br />

Se: 55%; Sp: 76%;<br />

PPV: 0.9; NPV: 0.29<br />

Low<br />

Incomplete<br />

data<br />

reporting.<br />

Bias from<br />

diagnosis and<br />

treatment<br />

possible<br />

The table continues on the next page<br />

KAPITEL 5 • Riskbedömning<br />

267

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